Main efficacy and function of pharmaceutical grade lanolin

 Main functions and functions of pharmaceutical grade lanolin YangmaozhiLanolin [8006-54-0] This strain is obtained by processing and refining wool
.

【Properties】This product is light yellow to brownish-yellow waxy substance; sticky and slippery; weak and specific odor
.

This product is easily soluble in tri-or medium, soluble in hot ethanol, very slightly soluble in ethanol, and insoluble in water; but it can be evenly mixed with about 2 times the amount of water
.

Melting point The melting point of this product (General Principle 0612 Second Method) is 36～42℃
.

Acid value The acid value of this product (general rule 0713) should not be greater than 1.
5
.

Iodine value The iodine value of this product (general rule 0713) should be 18 to 35 (the time it should be placed in a dark place for measurement is 4 hours)
.

Saponification value The saponification value of this product (general rule 0713) should be 92 to 106 (the heating and refluxing time is 2 hours during measurement)
.

[Identification] Take 0.
5g of this product, add 5ml to dissolve, add 1ml of acetic anhydride and 2 drops of sulfuric acid, it will turn dark green
.

　　[Check] Take 10g of this product for pH, add 50ml of water, heat and melt it on a water bath, stir continuously, let it cool, remove fat, the solution should be clear, take 10ml, add 1 drop of phenolphthalein indicator solution, it should not be red; take another 10ml, add 1 drop of methyl red indicator solution should not be red
.

　　Chloride Take 0.
20g of this product, put it in a conical flask, add 27ml of ethanol, heat to reflux for several minutes, let it cool, add 0.
5ml of nitric acid, filter, add 5 drops of silver nitrate ethanol solution (1→50) to the filtrate, If turbidity occurs, it should not be more concentrated (0.
035%) compared with the control solution [take 20ml of ethanol, add 7.
0ml of standard sodium chloride solution, 0.
5ml of nitric acid and 5 drops of ethanolic solution of silver nitrate (1→50)]
.

　　Easily oxidized Take 10ml of the solution left over from the above pH item, add 1 drop of potassium permanganate titration solution (0.
02mol/L), the red color should not disappear completely within 5 minutes
.

　　Insoluble matter in ethanol Take 0.
50g of this product, add 40ml of anhydrous ethanol, boil, and the solution should be clear or slightly turbid
.

　　Weight loss on drying Take this product and dry it at 105℃ to constant weight, while stirring, the weight loss should not exceed 0.
5% (General Rule 0831)
.

　　Residues on ignition shall not exceed 0.
15% (General Rule 0841)
.

　　【Category】Medicinal excipients, ointment bases and emulsifiers,
etc.

　　【Storage】Sealed and kept in a cool place
.