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Ma Jinbiao/Gan Jianhua's research group cooperated to analyze the molecular mechanism of the dual activity of RNA polymerase QDE-1 in the two-barrel family
On August 30, 2022, the international journal "Nucleic Acids Research" published online the research results of the research group of Prof.
In this study, a total of five complex structures of QDE-1 and different substrates in different reaction states were analyzed: DNA/RNA-templated extension complex (EC), de novo synthesis initiation complex (IC), initial NTP loading and structure containing two starting NTPs
Figure 1.
Figure 2.
Dr.
Paper link: https://doi.