Low doseof naloxone improves symptoms of cloned disease
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Last Update: 2020-07-06
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Source: Internet
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Author: User
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a clinical trial released by Penn State University in the United States shows that low-dose opioid antagonanos (naltrexone) can safely and effectively improve the symptoms associated with crohn's diseaseThe trial, compared to a low dose of naloxone (4.5 mg) and a 50 mg dose (FDA-approved treatment dose for drug abuse), showed that 89 percent of the 17 patients with moderate to severe cloned disease in the low-dose group had significantly reduced symptoms (a 70-point decrease in activity) and 67 percent of patients had their symptoms alleviated at one stage in a 16-week trial (Crohn's disease activity index reached 150 or lower)DrJill Smith, of The Hershey Medical Center at Penn State University School of Medicine, said low doses of naloxone have a significant advantage over current cloned disease treatmentsTraditional therapeutic drugs, such as steroid hormones, suppress the immune system and cause other serious side effects, while synthetic drugs and anti-
tumorsthe necrosis of the cause of death of the single-clone antibody Infliximaab (Infliximab) that inhibits the immune systemIn addition, bioproducts are expensive and must be injected with drugsLow doses of naloxone did not cause significant side effects in the initial study, no obvious immunosuppressive effects, and the cost of taking the drug was less than $100 per month and only needed to be taken once a day orally(Liu Ying)
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