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Tumors are important diseases that threaten human health, and cellular immunotherapy is bringing new hope
The tumor microenvironment is very important
On August 22, 2022, the team of Professor Liu Guangwei of the School of Life Sciences, Associate Professor Yang Hui of Fudan University, and researcher Bi Yujing of the Academy of Military Medical Sciences collaborated on eLife to publish a research paper
The study used Piezo1-specific DC-deficient mice (Piezo1-/-) and found that Piezo1-/-mice tumors grew faster and larger
This study used a variety of transgenic mice to combine cell biology and molecular biology techniques to find that the mechanical force receptor Piezo1 plays a regulatory role in DC-mediated T cell subset differentiation and has clinical application prospects
Professor Liu Guangwei of the School of Life Sciences of Beijing Normal University and researcher Bi Yujing of the Academy of Military Medicine are co-corresponding authors
Original link: https://elifesciences.
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