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Leukemia Res: Anaggrel for thrombocytopenia in polycythemia vera: insights into practicality and safety outcomes from a large multicenter database

 Last Update: 2022-09-20
 Source: Internet
 Author: User

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Anagrel (ANA) is a platelet-specific cytopenia that is mostly used in guidelines for high-risk primary thrombocytosis

The study used an established database of 527 PV patients from 10 institutions in the

Figure 1: Flowchart

Figure 2: Kaplan-Meier curve

Although ANA effectively lowers the median platelet count, it is 43

Table: Induced events

Overall, current research suggests that, despite limited tolerance, ANA remains an effective option for

Original source:

Rippel N, Tremblay D, Zubizarreta N, Podoltsev N, Gotlib J, Heaney M, Kuykendall A, O'Connell C, Shammo JM, Fleischman A, Kremyanskaya M, Hoffman R, Mesa R, Yacoub A, Mascarenhas J.

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