 Home > Active Ingredient News > Blood System > Lancet Haematol: Iberdomide plus dexamethasone for relapsed/refractory multiple myeloma

Lancet Haematol: Iberdomide plus dexamethasone for relapsed/refractory multiple myeloma

 Last Update: 2022-10-12
 Source: Internet
 Author: User

Tags

lovenox 40 mg

memantine 10 mg

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Iberdomide is a novel cerebellar E3 ligase modulator that has a stronger killing of tumor cells and immunostimulatory effects

This multi-cohort, open-label Phase 1/2 trial in Europe, Canada, and the United States enrolled multiple myeloma patients aged 18 years and older who

Between 5 December 2016 and 16 December 2020, the condition of 460 patients was evaluated, of whom 197 were enrolled in the group and received Iberdomide+ dexamethasone (90 in dose-increasing cohorts and 107 in dose-extended cohorts).

As of 2 June 2021, the dose-increasing cohort and the dose-extended cohort were followed up for a median of 5.

The most common adverse reactions of grade 3 and above were neutropenia (45%), anemia (28%), infection (27%), and thrombocytopenia (22%)

Overall, Iberdomide plus dexamethasone is generally safe in a large number of patients with multiple myeloma who have been pretreated and exhibit meaningful clinical activity that merits further evaluation

Original Source:

Sagar Lonial, et al.

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

SULODEXIDE 99% Almost White Powder Dideu-01112 Dideu

CAS No.: 57821-29-1

Pharmacy Grade

$61.76/G EXW

Heparin sodium 9041-08-1 vials safe delivery

CAS No.: 9041-08-1

Pharmacy Grade

$1/G EXW

Gadusol Powder Gadusol76663-30-4

CAS No.: 76663-30-4

Industrial Grade

$1-1.01/G FOB

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.