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Lactic acid is involved in the regulation of obesity-induced insulin resistance

 Last Update: 2022-02-20
 Source: Internet
 Author: User

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On January 14, 2022, the research group of Chen Yan from Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences published an online article entitled "Lactate is a key mediator that links obesity to insulin resistance via modulating cytokine production from adipose tissue" in Diabetes , a well-known international journal in the field of diabetes.

Lactic acid is the end product of glycolysis, a common metabolic intermediate in the body, and is also considered to be a small signaling molecule involved in the regulation of various cellular functions

Chen Yan's research group studied the monocarboxylic acid transporter MCT1, which is highly expressed in adipocytes, which is the most important lactate transporter in the body

This study revealed that lactic acid metabolism in adipose tissue is a key molecule linking obesity and insulin resistance in the process of obesity.

Researcher Chen Yan from Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences is the corresponding author of the paper, and doctoral student Lin Yijun is the first author of the paper

Article link: https://pubmed.

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Diabetes: Chen Yan's team found that lactic acid is involved in regulating obesity-induced insulin resistance

02-21

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Lactic acid is involved in the regulation of obesity-induced insulin resistance

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Diabetes: Chen Yan's team found that lactic acid is involved in regulating obesity-induced insulin resistance