Knowledge about gas chromatography

Gas chromatography-mass spectrometry technology, referred to as gas chromatography, that is, gas chromatography and mass spectrometer through the interface components to connect, gas chromatography as a means of sample separation, preparation, mass spectrometry as an online detection means of gas chromatography, quantitative analysis, supplemented by the corresponding data collection and control system to build a chromatography-mass spectrometry technology
.

Gas chromatography technology is to use the difference in the distribution coefficient of different compounds in the mobile phase (carrier gas) and stationary phase at a certain temperature, so that different compounds flow out of the column in chronological succession, so as to achieve the purpose of
separation analysis.

A gas chromatograph is a gas operating system, so the tightness of the instrument is very important
.

(1) Column change: The length of the capillary column entering the mass spectrometry cavity is not appropriate, too long or too short is not enough
.

(2) The gasket should be tight and appropriate, too loose will have the hidden danger of air leakage, too tight will crush the gasket, and a new sealing gasket
needs to be replaced every time the column is replaced.

(3) When cleaning the ion source, pay attention to its tightness
after opening the cavity.

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