Kangyuan pharmaceutical won the national science and technology progress award again

On January 8, good news came from the 2015 National Science and technology award conference: Kangyuan Pharmaceutical Co., Ltd led to complete the project of "establishment and application of quality standard system related to efficacy of modern Chinese medicine with Guizhi Fuling Capsule as the model" and won the second prize of national science and technology progress This is the only selected project in the field of medicine in Jiangsu Province, and Kangyuan pharmaceutical won the national science and technology progress award again after the project of "establishment and application of chemical research system of traditional Chinese medicine resources" in 2011 The national science and technology progress award is the highest recognition of innovation achievements in China In recent years, the level of quality standard of Chinese patent medicine has been constantly improved, and the content control of single index component is more and more However, the existing quality control technology of traditional Chinese medicine is difficult to achieve the basic attributes of "safe, effective and quality controllable" The quality control of traditional Chinese medicine is still the main bottleneck restricting the modernization and internationalization of traditional Chinese medicine In this context, Kangyuan pharmaceutical launched the project of "establishment and application of quality standard system related to efficacy of modern Chinese medicine with Guizhi Fuling Capsule as the model" Through the research of this project, Kangyuan pharmaceutical took Guizhi Fuling Capsule as an example, first proposed and constructed the quality control system related to compound Chinese medicine and efficacy, realized the quality control of the whole production process with the quality control goal of "the consistency of efficacy substance group and clinical efficacy", significantly improved the quality uniformity of Chinese patent medicine, guaranteed the effectiveness, and obtained It is widely recognized at home and abroad, which provides a demonstration for the modern research of compound Chinese medicine and the transformation of large varieties of Chinese patent medicine, and promotes the improvement of the standardization level of traditional Chinese medicine and the process of modernization and internationalization of traditional Chinese medicine Different from other science and technology awards, the national science and technology progress award pays more attention to the scientific research achievements of human development As a leading enterprise in the innovation of traditional Chinese medicine in China, Kangyuan pharmaceutical industry integrates national scientific research platforms such as the National Key Laboratory of new technology in the pharmaceutical process of traditional Chinese medicine and the national technology center of certified enterprises It has established a professional R & D institution for the development of innovative traditional Chinese medicine and common key technologies in the industry, Jiangsu Kangyuan modern Chinese Medicine Research Institute, and a scientific research team of nearly 300 people, with a proportion of more than 60% It has built more than 10 laboratories with well-known domestic scientific research institutes to realize resource sharing and technology complementarity The powerful scientific research force makes Kangyuan pharmaceutical become the leading enterprise of scientific and technological innovation in Chinese medicine industry Up to now, 81 research papers have been published in the project, including 26 SCI papers and 627 citations 11 Chinese invention patents, 10 foreign invention patents and 2 software copyrights were obtained The project research model has been successfully applied to 7 large varieties of traditional Chinese medicine in the completed units and other enterprises, which has significantly improved the quality uniformity of these 7 varieties; and it has been used in the preparation and quality control of phase II clinical samples in the United States, which has met the FDA's requirements of "quality, stability and uniformity" of botanical drugs The clinical research results show that Guizhi Fuling Capsule has a definite effect on the treatment of primary dysmenorrhea At the same time, the quality standards of 6 varieties of Guizhi Fuling Capsule using the quality control system were listed in Chinese Pharmacopoeia 2015, which provided a demonstration for the establishment of national standards The research results of the project have also been selected as the theme report of the conference by more than 10 large-scale academic conferences at home and abroad, and several well-known media such as China Journal of traditional Chinese medicine have also made special reports.