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Kangfang Biology is rapidly advancing the phase II clinical study of IL-4Rα monoclonal antibody atopic dermatitis and asthma

 Last Update: 2021-12-04
 Source: Internet
 Author: User

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Hong Kong, October 15, 2021/PRNewswire/ - Recently, Kangfang Bio (9926.

At the same time, the global phase II clinical trial of AK120 for the treatment of moderate to severe atopic dermatitis (AD) has completed the enrollment of the first patient in the first research center in the United States, and the research is progressing rapidly

IL-4 and IL-13 are key drivers of type 2 inflammation

In terms of safety, AK120 has completed a single-dose escalation phase Ia clinical study in healthy subjects and a multi-dose escalation phase Ib clinical study for the treatment of atopic dermatitis in New Zealand and Australia

In terms of effectiveness, early clinical studies have shown that AK120 has a potential clinical efficacy comparable to or better than Dupliu in patients with atopic dermatitis

Currently, China still lacks independent intellectual property rights for the treatment of moderate to severe asthma and moderate to severe atopic dermatitis biologics approved for marketing, and there is strong clinical demand

IL-4Rα monoclonal antibody is considered to be an important target for the treatment of allergic diseases, and it is also one of the best-selling antibody protein drugs in the autoimmune field.

About AK120

AK120 is a new type of autoimmune disease treatment drug that targets IL-4Rα independently developed by Kangfang Biology.

About Kangfang Bio

Kangfang Bio (HKEx stock code: 9926.

Source: Kangfang Bio

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