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Junshi Bio's KRAS inhibitor approved for clinical use

 Last Update: 2022-04-21
 Source: Internet
 Author: User

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On March 28, the CDE official website showed that Junshi Bio's KRAS inhibitor JS116 applied for clinical application in China for the first time

JS116 is a small-molecule, irreversible covalent inhibitor of KRASG12C with a new structure for the treatment of patients with KRASG12C-mutated non-small cell lung cancer (NSCLC)

In November 2020, the company signed the "Technology License and Cooperation Agreement" with Chengdu Huajian Future Technology Co.

Although the world's first KRAS inhibitor was only approved by the FDA in May 2021, based on the excellent potential in this field, there are already many companies deployed, and the competition is quite fierce.

KRASG12C target details

From: Insight database (http://db.

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