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Brain stroke patients within a few years after the event, cognitive ability and daily function showed a decline in acute and accelerated
.
This decline is mainly due to accumulated cerebral small vessel disease, neurodegeneration and inflammation
Stroke Vascular Prevention
Some studies have indeed proven the decline in cognition and daily functioning in the years before stroke
.
However, some knowledge gaps have not yet been resolved
In this way, Alis Heshmatollah of Erasmus MC University in Rotterdam and others used the famous Rotterdam study to evaluate the long-term temporal patterns of cognitive and daily function decline before and after stroke
.
It also further assessed whether gender, APOE genotype, and education level changed these trajectories
Continuous monitoring of medical records is used to evaluate incidental strokes until 2018
.
We matched participants who had a stroke with participants who did not have a stroke based on gender and year of birth (1:3)
They found that during an average follow-up of 12.
5 ± 6.
8 years, a total of 1,662 participants suffered their first stroke
diagnosis
The important significance of this long-term follow-up study is that compared with people without a stroke, patients with a stroke have a sharper decline in cognitive and daily function 10 years before the first stroke
.
This indicates that the accumulation of lesions in the brain has had a clinical impact before the stroke
Compared with people without a stroke, patients with a stroke 10 years before the first stroke, compared with people without a stroke, patients with a stroke 10 years before the first stroke,
Original source
Heshmatollah A, Dommershuijsen LJ, Fani L, Koudstaal PJ, Ikram MA, Ikram MK.
Long-term trajectories of decline in cognition and daily functioning before and after stroke.
J Neurol Neurosurg Psychiatry.
2021 Jul 6: jnnp-2021-326043 .
doi: 10.
1136/jnnp-2021-326043.
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