JES: SARS-CoV-2 may damage the endocrine function of the host body

, July 4, 2020
/PRNewswire/ -- In a recent study published in the journalJournal of Endocrine Society
, scientists from institutions such as the National Hospital of Sri Lanka found that COVID-19 infection can exacerbate endocrine disorders in patients with diseasePhoto Source: Pixabay/CC0 Public Domain
Researcher Dr Noel Prathepan Somasundaram said: 'We studied the previous SARS outbreak caused by very similar SARS-CoV-1 to provide some guidance for endocrinologists in treating COVID-19 patients;SARS-CoV-2 will induce the loss of the sense of smell and enter the host brain, in the previous process of coronavirus infection such as SARS-CoV-1, many patients will develop fatigue syndrome after the infection, which may be due in part to the body's adrenal dysfunction, that is, the adrenal glands can not produce enough cortisol to cause damage to the pituital function, during SARS epidemic, adrenal decline patients will generally recover within a yearresearchers say testing for cortisol deficiency and using steroids for treatment may be an important treatment, and recent studies have shown that using the steroid dexamethasone to treat patients with COVID-19 may reduce mortality in patients with severe illnessCOVID-19 also triggers new cases ofdiabetesand promotes the deterioration of the disease in patients withdiabetes, SARS-CoV-2 binds to cellular ACE2 receptors into cells and interferes with the production of insulin in the body, promoting elevated blood sugar levels in some patients, so monitoring and controlling blood sugar levels in the body of COVID-19 patients may also be an effective strategy to promote recoveryfinally, the researchers point out that people with vitamin D deficiency may be susceptible to COVID-19, while extra vitamin D supplementation may improve the patient's prognosis, although the current research evidence is mixed, and later researchers will continue to delve into how coronaviruses damage the function ingenocism of the host body(BioValleyBioon.com)original origins:Noel Pratheepan Somasundaram, Ishara Ranathunga, Vithiya Ratnasamy, et al.
The Impact of SARS-Cov-2 Virus on the Endocrine System,Journal of the Endocrine Society(2020)DOI: 10.1210/jendso/bvaa082