echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Antitumor Therapy > JAMA's latest guidelines: Colorectal cancer tends to be younger, and the starting age for screening drops to 45 years old

    JAMA's latest guidelines: Colorectal cancer tends to be younger, and the starting age for screening drops to 45 years old

    • Last Update: 2021-06-01
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    Colorectal cancer has always been a malignant disease with a very high fatality rate.

    According to the "China Colorectal Cancer Diagnosis and Treatment Standards (2020 Edition)" issued by the National Health Commission of China: "The 2018 China Cancer Statistics Report shows that the incidence and mortality of colorectal cancer in China ranks third and the third among all malignant tumors, respectively.
    There are 5, with 376,000 new cases and 191,000 deaths; cities are much higher than those in rural areas, and the incidence of colon cancer has risen significantly.
    Most patients are in the middle and advanced stages at the time of diagnosis.

    "From this point of view, regular screenings should be carried out .
    To prevent and diagnose colorectal cancer is a general trend and imminent.

    Recently, the US Preventive Services Task Force (USPSTF) released the latest colorectal cancer screening guidelines in JAMA.
    The latest guidelines are updated based on the old screening guidelines released in 2016, and the screening start age The age range recommended for colorectal cancer screening has been further expanded from 50-75 years old in 2016 to 45-75 years old.

    doi:10.
    1001/jama.
    2021.
    6238 According to the latest guidelines, the 65-74-year-old age group is most commonly diagnosed with colorectal cancer.
    It has become the third leading cause of cancer death in the United States.
    It is estimated that 52,980 people will die in 2021.
    In colorectal cancer.

    The guideline data shows that in the United States, 10.
    5% of new colorectal cancer cases are concentrated in people under 50.
    At the same time, from 2000-2002 to 2014-2016, the incidence of colorectal cancer among people aged 40-49 has increased.
    Nearly 15%.

    In 2016, 25.
    6% of American adults of school age had never been screened for colorectal cancer, but in 2018, the proportion rose again, and 31.
    2% of the population did not receive screening in time. As the incidence of colorectal cancer is getting younger, the USPSTF combined with multiple investigations and studies, and pointed out in the guidelines that age is one of the most important risk factors for the onset of colorectal cancer, and the incidence rate increases with age.
    At present, 94% of the The incidence of colorectal cancer is concentrated in adults over 45 years of age.

    Therefore, groups with a family history of colorectal cancer, male groups, people with other diseases (such as obesity, diabetes), and people with disturbances in daily life (long-term smoking, alcoholism) are highly likely to develop colorectal cancer.
    All should be screened regularly from the age of 45.

    The guidelines also point out that even asymptomatic adults who do not belong to the above-mentioned population should be screened for colorectal cancer from the age of 45.

    In the latest guidelines, the USPSTF recommends two screening methods: stool test and visual test, and gives the frequency of screening, among which: ▷ Stool test includes High-sensitivity gFOBT test (High-sensitivity gFOBT), immunochemical test (Faecal Immunochemical Test, FIT) and stool DNA immunochemical test (sDNA-FIT); ▷ Visual tests include colonoscopy, CT colonography, flexible sigmoidoscopy, and sigmoidoscopy Testing + FIT combined testing.

    The frequency of each screening method is as follows: USPSTF recommended screening methods and precautions USPSTF recommends that because various screening methods require different screening frequencies, screening locations, and preliminary preparations, at the same time, anesthesia or sedation during the inspection The methods and procedures that are followed after abnormalities are found are different.
    Both clinicians and patients should consider various factors to choose the most appropriate screening method. At present, the trend of rejuvenation of diseases seems to be more and more obvious.
    This is a wake-up call for each of us.
    In addition to maintaining a good and healthy life>End reference materials: [1]
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.