JAMA Psychic: Relationship between family health during pregnancy and neurodevelopment of the brain in children

The family is the cradle of children's growth.
happy family is the most important condition for children's physical and mental health development.
families with adverse problems often have a negative impact on children's physical and mental development, so that children suffer from trauma, serious will make children mentally biased, harm for life.
therefore, parents must pay attention to the mental health of children from poor families and understand their psychological characteristics, and use the right methods to educate and guide children so that they can grow up healthy like other children.
poor family relationships, also known as inse every family, can be expressed but not limited to family members confrontation, lack of cohesion, poor organizational and communication quality.
on adolescent mental health has been increasing in recent years, and the study of family factors has been paid more and more attention.
Although more and more related problems have been addressed, scientists remain wondering why (1) these negative effects persist throughout childhood, (2) at what age group children are most vulnerable to adverse family functions, and (3) whether this is generally applicable to poor family function in the general population.
, a powerful stressor associated with family insems, may be long-term and associated with a person's later well-being.
to explain the extent to which the continuing association between prenatal home dysplia and pre-adolescent problem behavior is mediated by under-cortical development, a team of experts from Harvard Medical School in the United States conducted a series of studies.
the results were published in the latest journal JAMA Psy.
the study was a population-based, multiracial population queue study starting in the fetal period, conducted from 2002-04-2006-01.
all pregnant women living in Rotterdam, the Netherlands, with a expected birth date between 2002-04-2006-01, are invited to participate.
8,879 pregnant women who participated during pregnancy excluded 1,266 mothers without partner data and 490 mothers with missing family function data, as well as 1 sibling out of 32 pairs of twins.
sample consisted of 2583 pairs of mothers and children.
poor family function of the father or mother is measured by the family assessment scale.
high-resolution structural neuroimaging data from 10-year-olds were collected using a single 3-T magnetic resonance imaging system.
children's emotional and behavioural problems with a child behaviour checklist.
hypothesis of the study is that prenatal family function is associated with smaller sea mass and amygdala volume in later childhood.
results included data on 2,583 children (average age 10.1 years; 1,315 girls . . . 50.9 per cent).
parents included 2,583 mothers and 1,788 fathers.
imagery suggests that children exposed to adverse family function reported by prenatal mothers have smaller sea mass (B -0.08; 95% CI, -0.13 to -0.02) and pillow leaves (B - -0.70; 95% CI, -1.19 to -0.21) volume before puberty.
there is no evidence that exposure to poor family function in children in the middle and late stages is associated with brain morphology.
addition, after adjusting for the mixing factors, the sea mass partially mediated the association between poor family function reported by prenatal mothers and pre-adolescent problem behavior (B s 0.08; 95% CI, 0.03-0.13).
a comprehensive assessment of mother's and father's family functions showed similar results, but the correlation was mainly related to the mother-related family function score.
, the study showed that prenatal mothers reported poor family function associated with smaller sea mass in pre-adolescent children.
differences in brain structure may be the root cause of behavioral problems, or it may be a manifestation of the long-term effects of the family environment on children's neurodevelopment.
: Xerxa Y, et al. Association of Poor Family Functioning From Pregnancy Onward With Preadolescent Behavior and Subcortical Brain Development. JAMA Psychiatry. 2021; 78(1):29–37. doi:10.1001/jamapsychiatry.2020.2862MedSci Original Source: MedSci Original Copyright Notice: All noted on this website "Source: Mets Medicine" or "Source: MedSci Original" text, images and audio and video materials, copyrights are owned by Metz Medical, without authorization, no media, website or individual may reproduce, authorized to reproduce with the words "Source: Mets Medicine".
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