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    Home > Active Ingredient News > Study of Nervous System > JAMA Neurology: Mild brain trauma should not be underestimated, CT should be reviewed regularly within 1 year

    JAMA Neurology: Mild brain trauma should not be underestimated, CT should be reviewed regularly within 1 year

    • Last Update: 2021-07-30
    • Source: Internet
    • Author: User
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    Computed tomography (CT) of the head with a positive result for acute intracranial hemorrhage is the gold standard diagnostic biomarker for acute traumatic brain injury (TBI)
    .


    In moderate to severe TBI (Glasgow Coma Score [GCS] score 3-12), some CT features have been shown to be related to prognosis


    Computed tomography (CT) of the head with a positive result for acute intracranial hemorrhage is the gold standard diagnostic biomarker for acute traumatic brain injury (TBI)


    In order to study whether the different types of intracranial injury after mild head injury (mTBI) are related to the prognosis, Esther L.


    The study recruited TBI patients 17 years of age and older with GCS scores of 13 to 15 who attended the emergency department of 18 primary trauma centers in the United States from February 26, 2014 to August 8, 2018, and were in TBI.
    Receive head CT imaging within 24 hours
    .


    The Glasgow Prognostic Extension Scale (GOSE) score was assessed at 2 weeks, 3, 6 and 12 months after injury


    The study recruited TBI patients 17 years of age and older with GCS scores of 13 to 15 who attended the emergency department of 18 primary trauma centers in the United States from February 26, 2014 to August 8, 2018, and were in TBI.


    The main results and measurement indicators are frequency, comorbidity and clustering of CT features; incomplete recovery (GOSE score <8 vs 8); adverse outcomes at 2, 3, 6 and 12 months (GOSE score < 5 vs≥5)


    There were 1935 mTBI patients (mean [SD] age, 41.


    Different subtypes of acute intracranial hemorrhage

    Different subtypes of acute intracranial hemorrhage

    Contusion, subarachnoid hemorrhage and/or subdural hematoma characteristics and incomplete recovery at 12 months after injury (GOSE score <8 years of odds ratio [ORs]: RACK-TBI, 1.
    80 [95% CI, 1.
    39 -2.
    33]; CENTER-TBI, 2.
    73[95%CI, 2.
    18-3.
    41]) and a greater degree of adverse outcomes (Odds ratio at GOSE score <5 years: RACK-TBI, 3.
    23[95%CI, 1.
    59-6.
    58 ]; CENTER-TBI, 1.
    68 [95% CI, 1.
    13-2.
    49]) related , but epidural hematoma has nothing to do with this
    .

    Contusion, subarachnoid hemorrhage and/or subdural hematoma characteristics and incomplete recovery at 12 months after injury (GOSE score <8 years of odds ratio [ORs]: RACK-TBI, 1.
    80 [95% CI, 1.
    39 -2.
    33]; CENTER-TBI, 2.
    73[95%CI, 2.
    18-3.
    41]) and a greater degree of adverse outcomes (Odds ratio at GOSE score <5 years: RACK-TBI, 3.
    23[95%CI, 1.
    59-6.
    58 ]; CENTER-TBI, 1.
    68 [95% CI, 1.
    13-2.
    49]) related , but epidural hematoma has nothing to do with this
    .


    Intraventricular and/or petechiae hemorrhage is associated with greater adverse outcomes within 12 months after injury (for example, GOSE score in TRACK-TBI <5 at 1 year: 3.
    47 [95% CI, 1.
    66-7.
    26])
    .


    Some CT features are more closely related to prognosis than previously verified variables (for example, 1-year ORs with GOSE score <5 in TRACK-TBI: neuropsychiatric history, 1.


    Intraventricular and/or petechiae hemorrhage is associated with greater adverse outcomes within 12 months after injury (for example, GOSE score in TRACK-TBI <5 at 1 year: 3.


    In summary, mTBI mTBI 1 year pathologic CT features have different effects on the prognosis to injury after


    Original source

    Yuh EL, Jain S, Sun X, et al.


    Yuh EL, Jain S, Sun X, et al.
    Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury : A TRACK-TBI Study With External Validation in CENTER-TBI.
     JAMA Neurol.
     Published online July 19, 2021.
    doi:10.
    1001/jamaneurol.
    2021.
    2120 Yuh EL, Jain S, Sun X, et al.
    Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury JAMA Neurol.
    JAMA Leave a message here
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