JAMA Netw open: The relationship between serum uric acid level and renal macrovascular and microvascular dysfunction

Atherosclerotic diseases are common in the general population, such as coronary artery disease (CAD), peripheral artery disease (PAD) and brainVascular diseases, and often complicated by acute coronary syndrome, severe limb ischemia and cerebrovascular accidents

Atherosclerotic diseases are common in the general population, such as coronary artery disease (CAD), peripheral artery disease (PAD) and brainVascular diseases, and often complicated by acute coronary syndrome, severe limb ischemia and cerebrovascular accidents

In Eurasian populations, serum uric acid (SUA) levels are associated with vascular dysfunction, but for sub-Saharan African populations, this correlation is poorly understood.

Analyze the correlation between SUA and microvascular (proteinuria) and macrovascular (peripheral artery disease and coronary artery disease) dysfunction through Logistic regression, and adjust age, gender, estimated glomerular filtration rate, residence location, socioeconomic status, Alcohol, smoking,Diabetes , hypertension, waist-to-hip ratio and totalCholesterol level

Analyze the correlation between SUA and microvascular (proteinuria) and macrovascular (peripheral artery disease and coronary artery disease) dysfunction through Logistic regression, and adjust age, gender, estimated glomerular filtration rate, residence location, socioeconomic status, Alcohol, smoking,Diabetes , hypertension, waist-to-hip ratio and totalCholesterol level

A total of 4919 Ghanaians (3,047 [61.

The relationship between SUA and dysfunction of large blood vessels and renal microvascular

The relationship between SUA and dysfunction of large blood vessels and renal microvascular

This study shows that in the South African patient population, higher SUA concentrations are associated with renal microvascular dysfunction, but not with macrovascular dysfunction

This study shows that in the South African patient population, higher SUA concentrations are associated with renal microvascular dysfunction, but not with macrovascular dysfunction

References: Hayfron-Benjamin CF, van den Born B, Amoah AGB, et al.
Associations of Serum Uric Acid Levels With Macrovascular and Renal Microvascular Dysfunction Among Individuals From Sub-Saharan Africa.
 JAMA Netw Open.
2021;4(10):e2128985.
doi:10.
1001/jamanetworkopen.
2021.
28985 Hayfron-Benjamin CF, van den Born B, Amoah AGB, et al.
Associations of Serum Uric Acid Levels With Macrovascular and Renal Microvascular Dys Among Function Individuals From Sub-Saharan Africa.
 JAMA Netw Open.
JAMA2021;4(10):e2128985.
doi:10.
1001/jamanetworkopen.
2021.
28985 doi:10.
1001/jamanetworkopen.
2021.
28985

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