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Many severe stroke patients have impaired airway protective reflexes, resulting in prolonged invasive mechanical ventilati.
Many severe stroke patients have impaired airway protective reflexes, resulting in prolonged invasive mechanical ventilati.
To test whether early tracheal intubation versus standard tracheal intubation can improve functional outcomes in stroke patients receiving mechanical ventilation, researchers from the University of Heidelberg, Germany conducted a randomized clinical trial involving 382 patients with severe acute ischemia receiving invasive ventilati.
Patients were randomly assigned at 26 neurocritical care centers in the United States and Germa.
Patients were randomly assigned at 26 neurocritical care centers in the United States and Germa.
RESULTS: Of the 382 randomized patients (median age, 59 years; 48% women), 366 (98%) completed the trial, with follow-up data for the primary outcome (177 patients [91%] in the early group); 189 patients [94%] in the standard grou.
There was no significant difference in the proportion of patients without severe disability (mRS score, 0-4) at 6 months between the early intubation group and the control group (45% vs 41%; difference, -6% [95% CI, -13] % to 2%]; OR = 93 [95% CI, 60-42]; P = 73.
In mechanically ventilated patients with severe stroke, the strategy of early tracheostomy did not significantly improve survival without severe disability after 6 months compared with the standard tracheostomy approa.
In mechanically ventilated patients with severe stroke, the strategy of early tracheostomy did not significantly improve survival without severe disability after 6 months compared with the standard tracheostomy approa.
references:
references:Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Tri.
Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Tri.
JA.
Published online May 04, 202 doi:11001/ja.
2024798 Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Tri.
JA.
Published online May 04, 202 doi:11001/ja.
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