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    Home > Active Ingredient News > Blood System > JAMA: Blinatumomab can improve the event-free survival rate of high-risk children with B-cell acute lymphoblastic leukemia who relapse for the first time

    JAMA: Blinatumomab can improve the event-free survival rate of high-risk children with B-cell acute lymphoblastic leukemia who relapse for the first time

    • Last Update: 2021-03-19
    • Source: Internet
    • Author: User
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    Researchers in children recently investigated the effect of replacing consolidation chemotherapy with Blinatumomab on the event-free survival rate of children with high-risk first recurrence of B-ALL before allogeneic hematopoietic stem cell transplantation.


    Recently, researchers have investigated the effect of replacing consolidation chemotherapy with Blinatumomab on the event-free survival rate of children with high-risk first recurrence of B-ALL before allogeneic hematopoietic stem cell transplantation.
    The event rates of the stem cell Blinatumomab group and the consolidation chemotherapy group were 31% and 57%, respectively (hazard ratio [HR]: 0.
    33) The event rates of the Blinatumomab group and consolidation chemotherapy group were 31% and 57%, respectively (hazard ratio [HR] : 0.
    33) For high-risk children with B-cell acute lymphoblastic leukemia who relapse for the first time, replacing the consolidation chemotherapy with Blinatumomab before allogeneic hematopoietic stem cell transplantation can significantly improve the event-free survival rate of the children.
    For high-risk children with B-cell acute lymphoblastic leukemia who relapse for the first time, replacing the consolidation chemotherapy with Blinatumomab before allogeneic hematopoietic stem cell transplantation can significantly improve the event-free survival rate of the children.
    Original source com/journals/jama/article-abstract/2776881" target="_blank" rel="noopener">Effect of Chemotherapy Blinatumomab VS-ON the Event as Free Survival Among Children With High-Risk-First Relapse the Cell Acute lymphoblastic Leukemia B-A Randomized Clinical Trial.
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