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JAHA: The relationship between blood pressure variability in the elderly and cognitive decline and the risk of dementia

 Last Update: 2021-08-01
 Source: Internet
 Author: User

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Blood pressure variability (BPV) in middle-aged people can increase the risk of dementia in later life, but the effect of BPV on the cognition of elderly people without major cognitive deficits is not yet clear
.

Recently, the heart blood vessels published on the prestigious journal JAHA areas of disease research article, researchers in the event of aspirin to reduce the elderly (ASPREE) test conducted post hoc analysis assessed the related long-term, visits BPV dementia and cognitive decline Risk
.

Heart blood vessels

ASPREE participants (N=19114) did not have dementia or severe cognitive impairment at the time of enrollment
.

At baseline and follow-up, the subjects’ blood pressure was measured and a standardized cognitive series was used to assess overall cognition, delayed episodic memory, language fluency, processing speed and attention

Cumulative incidence of dementia

Compared with the lowest tertile of BPV, individuals in the highest tertile of BPV have an increased risk of dementia and cognitive decline, which has nothing to do with average blood pressure and the use of antihypertensive drugs
.

There is evidence that gender changes the association with dementia events (interaction P=0.

It can be seen that older people without severe cognitive impairment (especially men) have higher BPV and are associated with increased risk of dementia and cognitive decline

Older people without severe cognitive impairment (especially men) higher BPV are associated with increased risk of dementia and cognitive decline

Original source:

Michael E.

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