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The number of myocardial infarction (MI) survivors has increased globally due to a demographic shift towards an older population and an increase in post-MI mortality
.
The risk of neurovascular complications such as ischemic stroke and vascular dementia is significantly increased in this growing population
myocardial infarction stroke vascular cholesterol
Researchers assessed the risk of Parkinson's disease and secondary Parkinson's disease in survivors of myocardial infarction (MI)
.
We conducted a population-based nationally matched cohort study between 1995 and 2016 using data from the Danish Medical Registry and identified all patients with a first-time diagnosis of MI
.
In addition, the researchers sampled gender-, age-, and year-matched general population comparison cohorts without MI
diagnosis
We identified 181,994 MI patients and 909,970 matched comparison cohort members (median age 71 years; 62% male)
.
After 21 years of follow-up, the cumulative incidence of Parkinson's disease in the MI cohort was 0.
CONCLUSIONS: MI was associated with a 20% lower risk of Parkinson's disease and a 28% lower risk of secondary Parkinson's disease
.
The reduced risk may reflect an inverse association between cardiovascular risk factors and Parkinson's disease
MI was associated with a 20% lower risk of Parkinson's disease and a 28% lower risk of secondary Parkinson's disease
Original source:
Jens Sundbøll.
