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In a study published today in JAHA, the leading journal in the field of cardiovascular disease, researchers aimed to compare estimated BMIs in patients with and without severe mental illness (SMI; bipolar disorder, schizophrenia, or schizoaffective disorder).
Cardiovascular risk at 10 and 30 years
.
The researchers included all patients aged 18 to 75 years who attended primary care between January 2016 and September 2018 and used diagnostic codes to classify them into those with and without SMI
.
We estimated ten-year cardiovascular risk using the Atherosclerotic Cardiovascular Disease Score in patients aged 40 to 75 years without cardiovascular disease, and the Framingham Risk Score for 30-year cardiovascular risk in patients aged 18 to 59 years without cardiovascular disease
diagnosis
The researchers collected demographic .
Descriptive statistics assessed unadjusted differences, while general linear models assessed differences for continuous variables and logistic regression models were used to assess categorical variables .
The model was then adjusted for age, gender, race, ethnicity and insurance type .
A total of 11,333 patients with SMI and 579,924 patients without SMI were included in the study
.
After adjustment for covariates, patients with SMI had a significantly higher 10-year cardiovascular risk (mean 9.
44%; 95% CI 9.
29%-9.
60%) compared with patients without SMI (mean 7.
CONCLUSIONS: A significant increase in cardiovascular risk associated with SMI is evident even in young adults .
This suggests the importance of addressing uncontrolled major cardiovascular risk factors early in patients with SMI .
.
This suggests the importance of addressing uncontrolled major cardiovascular risk factors early in patients with SMI
Original source:
Rebecca C.
Rossom.
et al.