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November 16, 2020 // -- Scientists from Monash University and others have found that obstructive sleep apnea (OSA, obstructive sleep apnea) may be directly related to high-risk dementia in a recent study published in the international journal Journal of Alzheimer's Disease entitled "Severe Obstructive Sleep Apnea With Associated With Brain Amyloid Burden: A Preliminary PET Imaging Study Study."
researcher Dr Melinda Jackson points out that severe obstructive sleep apnea may increase levels of β-amyloid protein, which accumulates on the walls of the body's brain arteries, increasing an individual's risk of developing dementia. In the
study, researchers included 34 patients recently diagnosed with untreated obstructive sleep apnea, as well as 12 patients with asymptomatic sleep disorders, who used PET brain scanning techniques to analyze the association between amyloid burden in the brain and sleep, demographic information, and emotional performance.
Photo Source: CC0 Public Domain researchers found that participants with obstructive sleep apnea showed higher amyloid burden, poorer sleep efficiency, and shorter N3 sleep periods, i.e. regeneration periods of body healing and self-healing.
Obstructive sleep apnea is a common sleep disorder that affects the health of about 1 billion people worldwide, often caused by an individual's collapsed airfway while sleeping, causing intermittent drops in the body's oxygen levels and waking individuals from sleep. Dr. Jackson, the
final researcher, said it was important to clarify the increase in amyloid levels in the brains of people with obstructive sleep apnea or to further study the link between more obstructive sleep apnea and increased risk of dementia later in life, and to help us develop more interventions to reduce an individual's risk of dementia by treating obstructive sleep apnea.
() Original source: Jackson, Melinda L, Cavuoto, Marinab, Schembri, Rachel, et al. Severe Obstructive Sleep Apnea Is Associated with Higher Brain Amyloid Burden: A Preliminary PET Imaging, Journal of Alzheimer's Disease (2020). DOI:10.3233/JAD-200571
