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    Home > Active Ingredient News > Immunology News > JACI: Parasitic infections may increase the risk of developing airway hyperresponsiveness in children

    JACI: Parasitic infections may increase the risk of developing airway hyperresponsiveness in children

    • Last Update: 2022-01-21
    • Source: Internet
    • Author: User
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    Many people should have the impression that in the 1970s and 1980s, many children had parasitic infections such as roundworms, but very few people had allergies


    Many people should have the impression that in the 1970s and 1980s, many children had parasitic infections such as roundworms, but very few people had allergies


    Infected Children Impact Factor

    The researchers searched relevant databases from January 1970 to January 2020


    The primary outcome was the incidence of allergic disease, including asthma, wheezing, rhinitis, eczema, and airway hyperresponsiveness (BHR); the secondary outcome was the clinical outcome of respiratory allergic disease, such as exacerbation, hospitalization, symptom severity, and Health-related quality of life


    Quality of Life

    Finally, 80 studies with 99,967 participants were included, most of which were children (n=47, 58.


    The researchers did not observe an overall link between parasitic infections and allergic disease


    Stratified for children or adults, a significant association between Ascaris infection and BHR was observed in children (RR=1.


    There is still no reliable evidence that parasitic infections play a role in asthma, wheezing, and eczema


    Original source:

    Arrais M, Maricoto T, Nwaru BI, Cooper PJ, Gama JM, Brito M, Taborda-Barata L, Helminth infections and allergic diseases: systematic review and meta-analysis of the global literature, Journal of Allergy and Clinical Immunology (2022), doi: https://doi.


    Helminth infections and allergic diseases: systematic review and meta-analysis of the global literature,



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