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    Home > Active Ingredient News > Study of Nervous System > JACC: A new treatment option for atrial fibrillation-predictors of device-related thrombosis after percutaneous left atrial appendage occlusion

    JACC: A new treatment option for atrial fibrillation-predictors of device-related thrombosis after percutaneous left atrial appendage occlusion

    • Last Update: 2021-07-27
    • Source: Internet
    • Author: User
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    Atrial fibrillation (atrial fibrillation) is an extremely common arrhythmia


    The prevalence of atrial fibrillation in the Chinese population with


    Thrombus oral warfarin or other new anticoagulant drugs is one of the options for preventing stroke and systemic embolism for patients with CHA2DS2-VASc score ≥ 2 points


    Many patients will basically or completely abandon anticoagulation therapy because of high bleeding risk, poor compliance, drug interactions, and economic problems


    As a safe and effective method, internal medicine percutaneous left atrial appendage occlusion (LAAO) can replace anticoagulants to prevent stroke and systemic embolism in patients with atrial fibrillation


    Device-related thrombosis (DRT) has always been considered a major problem of LAAO Achilles'


    Thirty-seven international centers provided LAAO cases with or without DRT (matched with DRT case equipment and time-dependent)


    The follow-up time of the DRT group and the non-DRT group was similar, with a median of 1.


    The main risk factors for DRT after LAAO

    The main risk factors for DRT after LAAO

    DRT was detected in 24.


    The presence of RT is associated with a 137% increase in the composite endpoint risk of death, ischemic stroke, or systemic embolism (HR=2.


    Five DRT risk factors: hypercoagulability (OR=17.


    The time to DRT after LAAO and the time to the main composite endpoint of LAAO

    The time to DRT after LAAO and the time to the main composite endpoint of LAAO

    After converting into risk factor scores, compared with patients without any risk factors, the risk of DRT in patients with a DRT risk score ≥ 2 increased by 2.


    Compared with patients without any risk factors, patients with DRT risk score ≥2 had a 2.


    It can be seen that DRT after LAAO is related to ischemic events


    references:

    Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion.


    Predictors of Device-Related Thrombus Following Percutaneous Left Atrial Appendage Occlusion.


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