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JAAD: How to distinguish irritant seborrheic keratosis from squamous cell carcinoma

 Last Update: 2021-11-02
 Source: Internet
 Author: User

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Dermatologists often make the wrong diagnosisof seborrheic keratosis (SK)
.

According to statistics, in a series of 4361 pathological cases clinically identified as SK or irritant seborrheic keratosis (ISK), 3759 (86.

Diagnosis ¹¹

In addition to determining whether a single lesion is benign or malignant, it must be recognized that SCC may develop within SK and not just appear as a random collision tumor
.

This phenomenon is more common in elderly men with a history of immunosuppression related to organ transplantation

Immune to AKT

In this issue of the Journal of the American Academy of Dermatology , Papageorgiou et al.
³ studied dermoscopy standards that can be used as a valid predictor of the differential diagnosis between ISK and SCC
.

A total of 104 SCCs and 61 ISKs were retrospectively analyzed

Journal of the American Academy of Dermatology ³³Vascular

So far, there is no clear way to distinguish between ISK and SCC
.

Richey et al ⁴ conducted a chemical analysis of immunohistochemistry, the ISK and SCC in situ (SCCIS) were compared

⁴⁴Lymphoma

The American Academy of Dermatology has established appropriate standards for use in an effort to control costs and provide effective medical care
.

Currently, I will classify immunoperoxidase staining to distinguish between ISK and SCC, and the American Academy of Dermatology has named it "uncertain applicability"

One day, we will distinguish between ISK and SCC around precise clinical and histopathological criteria
.

Literature source: Warren R.
Heymann, Irritated seborrheic keratosis versus squamous cell carcinoma: Circling in on their differentiation,
Journal of the American Academy of Dermatology,Volume 85, Issue 5,2021,Pages 1119-1120,
ISSN 0190-9622, https: //doi.

org/10.
1016/j.

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