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Cardiovascular disease is a serious complication of granuloma multivascularitis (GPA).
study analyzed the burden trends of coronary artery disease (CAD) and its two severity manifestations, acute myocardial infarction (AMI) and heart failure (HF), in a sample of GPA hospitalized patients.
researchers conducted a retrospective cross-sectional analysis using a sample of hospitalized patients in the country.
sample included GPA patients hospitalized from 2005 to 2014.
analyzed trends in CAD, AMI and HF ratios in all GPA inpatients compared to non-GPA patients.
use to adjust the logistic regression of potential confuse factors and include interactions.
of the 103,453 GPA inpatients, 20,351 (19.7%) were also diagnosed with CAD.
the overall burden of traditional cardiovascular risk factors in GPA patients with CAD was lower than in non-GPA patients with CAD, with the exception of chronic kidney disease (57% vs 21%).
the 10-year study period, CAD (from 16.6% in 2005 to 22.7% in 2014) and CAD with HF (from 2005 4.31 per cent rose to 9.88 per cent in 2014) but the AMI did not rise (from 1.17 per cent in 2005 to 1.11 per cent in 2014).
study found that CAD and CAD burdens associated with HF increased over a 10-year period compared to non-GPA, but AMI did not.
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