J Rheumatol: Correlation between improved disease activity scores in patients with childhood dermatitis and validated original disease activity scores
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Last Update: 2020-05-29
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Source: Internet
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Author: User
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Childhood dermatitis (JDM) is a rare disease that can be treated in children, but patients may be exposed to long-term effects of the diseaseClinical trials are needed to find better treatmentsThe empirical tool used clinically to assess disease activity is the Disease Activity Score (DAS), but not all clinics routinely collect this indicatorAn improved DAS (DAS mod) has been developed, an indicator that can be scored using data routinely collected by clinical staff and has been used in previous studiesThe purpose of this study was to determine whether DASmod was associated with proven DAS in JDM patientsin this study, dASmod (score 0-12) and DAS (score 0-20) were used in patients with JDMThe correlation between DASmod and verified DAS was analyzedthe median DASmod score (IQR) was 2.0 (0, 4.0) and the median DAS score (IQR) was 3.0 (0,5.5) among the 51 patients visited by the authors' JDM clinicThe scores of the two tools were highly positively correlated (r-0.94, p 0.001, 95% CI (0.89, 0.96))Linear regression is significant (R2 s 0.88, F (1,49) s 357.60, p 0.001), in this dataset, the tool can be used interchangeably with the regression equation: DAS score s-0.26-1.5-DAS modif the regression equation from this data set is successfully validated in future data sets, further collaboration between different data centers related to the activity of the collection of children's JDM disease will be facilitated
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