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In a recent study published in Journal Of Neurology Neurosurgery And psychic, an authoritative journal in the field of neurology, the study aims to identify baseline characteristics of patients who survive within six months of spontaneous cerebral hemorrhage (ICH) and new clinical events associated with decreased function.
the single-center study, the researchers looked at survivors six months after ICH, with an improved Rankin (mRS) score of 0-3.
researchers defined the decline in functionality by turning mrsS to 4-5.
used single- and multivariate models to assess the association between baseline characteristics and emerging clinical events and decreased functionality.
560 patients, 174 (31%) had an MSS score of 0-3 at 6 months.
during a nine-year mid-level follow-up period (IQR was 8.1-9.5), 40 (23%) patients had MRS to 4-5.
age, diabetes, ICH levels, and higher MRS scores at 6 months were independently associated with decreased function.
in baseline MRI markers, limited cerebral leaf micro-bleeding (CMB) and brain leaf and deep CMB joints were independently associated with decreased function.
new clinical events occurring during follow-up in the multivariate model, age (cause-specific HR (CSHR): 1.07; 95% CI: 1.03 to 1.11), ICH volume (CSHR:1.03; 95% CI: 1.01 to 1.06), mRS score at 6 months (1.61 per 1 point CSHR increase, 95% CI: 1.07 to 2.43), dementia (CSHR: 3.8) 1,95% CI: 1.78 to 8.16) and any stroke (CSHR: 4.29, 95% CI: 1.80 to 10.22) are still associated with MSS becoming 4-5 independent.
showed that nearly a quarter of patients with spontaneous ICH experienced decreased function over time.
factors were age, ICH volume, higher MRS score at 6 months, and new clinical events after ICH.
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