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J Dermatolog Treat: Budalumab effective in scalp/nail psoriasis

 Last Update: 2022-04-18
 Source: Internet
 Author: User

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It is estimated that nearly 80% of people with psoriasis will have scalp involvement

In AMAGINE-1, patients receiving budaluzumab 210 mg every 2 weeks (Q2W) or placebo for up to 12 weeks reported scalp clearance as measured by the Psoriasis Scalp Severity Index (PSSI)

Results showed that at week 12, more patients receiving budaluzumab achieved 75% and 100% improvement from baseline PSSI compared to placebo, and had lower mean PSSI over 12 weeks

Taken together, the results of this study suggest that budaluzumab use was associated with clearance of scalp psoriasis for up to 12 weeks, and improvement in nail psoriasis (including complete nail clearance) for up to 52 weeks.

Source:

Boni Elewski, et al.

Efficacy of brodalumab in the treatment of scalp and nail psoriasis: results from three phase 3 trials

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