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J Clin Oncol: Shocked!

 Last Update: 2021-05-08
 Source: Internet
 Author: User

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Esophageal cancer is a common medsci.

medsci.

According to the principle of radiotherapy and chemotherapy followed by surgery for esophageal cancer, preoperative radiotherapy and chemotherapy have become the standard treatment for patients with locally advanced resectable esophageal cancer or borderline cancer.

From 2004 to 2008, researchers randomly divided 366 patients into two groups and received carboplatin + paclitaxel (5 weeks/course) combined with radiotherapy (5 days a week, 23 times, total 41.

Overall survival rate

The median follow-up time was 147 months (interquartile range: 134-157).

The overall survival rate of patients receiving neoadjuvant chemoradiation is higher (hazard ratio [HR] 0.

Cumulative mortality from different causes

The 10-year absolute overall survival benefit is 13% (38% vs 25%) .

The 10-year absolute overall survival benefit is 13% (38% vs 25%)

Cumulative recurrence rate

Although it has a significant impact on isolated local recurrence (HR 0.

In short, according to the CROSS criteria, the overall survival benefit of patients with locally advanced resectable esophageal cancer or borderline cancer from preoperative radiotherapy and chemotherapy can last at least 10 years!

According to the CROSS criteria, the overall survival benefit of patients with locally advanced resectable esophageal cancer or borderline cancer from preoperative radiotherapy and chemotherapy can last at least 10 years! According to the CROSS criteria, the overall survival benefit of patients with locally advanced resectable esophageal cancer or borderline cancer from preoperative radiotherapy and chemotherapy can last at least 10 years!

Original source:

Eyck Ben M, van Lanschot J Jan B, Hulshof Maarten CCM et al.

org/10.
1200/JCO.
20.
03614" target="_blank" rel="noopener">Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial in this message

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