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Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma.
Lymphoma
This study is a prospective study of DLBCL elderly patients, which aims to prospectively verify the application of simplified elderly assessment (sGA) in diagnosis and integrate it into elderly patients with diffuse large B-cell lymphoma (DLBCL) In the prognostic score.
diagnosis
Total prognosis grouped by sGA
Total prognosis grouped by sGAA total of 1163 patients (median age 76 years) were enrolled, and the 3-year OS was 65% (95% CI 62-68).
In view of the fact that in the oGA multivariate analysis, age greater than 80 years old has an independent correlation with OS, the researchers also developed a new simplified version of GA (sGA), which can divide patients into appropriate (55%) and inappropriate (28%) and frailty (18%), the three-year OS was 75%, 58%, and 43%, respectively.
Total prognosis grouped by EPI
Total prognosis grouped by EPIIn addition, the researchers also identified three risk groups: low-risk group (23%), medium-risk group (48%), and high-risk group (29%).
In the low-risk group (23%), medium-risk group (48%) and high-risk group (29%), the estimated 3-year OS was 87%, 69%, and 42%, respectively.
In summary, the study of the elderly DLBCL project confirmed that sGA can be used as an objective tool to assess the health status of elderly patients with DLBCL, and defined a new EPI to predict the OS of elderly patients with DLBCL.
Original source:
Merli Francesco, Luminari Stefano, Tucci Alessandra et al.
org/10.
1200/JCO.
20.
02465" target="_blank" rel="noopener">Simplified Geriatric Assessment in Older Patients With Diffuse Large B-Cell Lymphoma: The Prospective Elderly Project of the Fondazione Italiana Linfomi.
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