echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Blood System > J Clin Oncol: Application of Simplified Elderly Patient Assessment Scale in DLBCL Elderly Patients

    J Clin Oncol: Application of Simplified Elderly Patient Assessment Scale in DLBCL Elderly Patients

    • Last Update: 2021-03-18
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma.


    Lymphoma

    This study is a prospective study of DLBCL elderly patients, which aims to prospectively verify the application of simplified elderly assessment (sGA) in diagnosis and integrate it into elderly patients with diffuse large B-cell lymphoma (DLBCL) In the prognostic score.


    diagnosis

    Total prognosis grouped by sGA

    Total prognosis grouped by sGA

    A total of 1163 patients (median age 76 years) were enrolled, and the 3-year OS was 65% (95% CI 62-68).


    In view of the fact that in the oGA multivariate analysis, age greater than 80 years old has an independent correlation with OS, the researchers also developed a new simplified version of GA (sGA), which can divide patients into appropriate (55%) and inappropriate (28%) and frailty (18%), the three-year OS was 75%, 58%, and 43%, respectively.


    Total prognosis grouped by EPI

    Total prognosis grouped by EPI

    In addition, the researchers also identified three risk groups: low-risk group (23%), medium-risk group (48%), and high-risk group (29%).


    In the low-risk group (23%), medium-risk group (48%) and high-risk group (29%), the estimated 3-year OS was 87%, 69%, and 42%, respectively.


    In summary, the study of the elderly DLBCL project confirmed that sGA can be used as an objective tool to assess the health status of elderly patients with DLBCL, and defined a new EPI to predict the OS of elderly patients with DLBCL.


    Original source:

    Merli Francesco, Luminari Stefano, Tucci Alessandra et al.


    org/10.
    1200/JCO.
    20.
    02465" target="_blank" rel="noopener">Simplified Geriatric Assessment in Older Patients With Diffuse Large B-Cell Lymphoma: The Prospective Elderly Project of the Fondazione Italiana Linfomi.
    Leave a message here
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.