J Clin Endocr Metab: how can hyperglycemia cause pancreatic cancer

August 8, 2019 / BIOON / - a study published in Journal of Clinical Endocrinology & Metabolism shows that hyperglycemia may increase the risk of pancreatic cancer This year, 45750 people (23800 men and 21950 women) will die of pancreatic cancer Pancreatic cancer is a disease in which healthy cells stop working normally and grow out of control The five-year survival rate for pancreatic cancer is only 9%, because the disease is difficult to diagnose, and it is usually not detected until the cancer spreads from the pancreas to other parts of the body Photo source: http://cn.bing.com "diabetes is one of the known risk factors for pancreatic cancer," said cheol young Park, MD, Samsung hospital, Seoul, South Korea, co-author of the study "When we used the national cohort database to assess the incidence rate of pancreatic cancer based on fasting blood glucose level, we found that the number of pancreatic cancer cases was also increasing with the increase of fasting blood glucose level This is true for both diabetics and nondiabetics "In this national study, researchers used a national cohort database containing about 25000000 patients to assess the incidence rate of pancreatic cancer in South Korea based on blood glucose levels They found that the incidence rate of pancreatic cancer increased significantly in the diabetic population as the blood sugar level increased, and also increased significantly in the prediabetes or normal blood glucose group "Our research shows that early detection of hyperglycemia in physical examination and improvement of blood glucose status through lifestyle changes may provide a key opportunity to reduce the risk of pancreatic cancer," Park said "Reference: cheol young Park et al The incremental risk of pancreative cancer accounting to fast glucose levels: national population based cohort study, Journal of Clinical Endocrinology & metabolism (2019) Doi: https://doi.org/10.1210/jc.2019-00033