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J CEREBR BLOOD FM: Cerebrospinal fluid hemoglobin promotes secondary brain injury related to subarachnoid hemorrhage

 Last Update: 2021-07-29
 Source: Internet
 Author: User

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Patients with aneurysmal subarachnoid hemorrhage (SAH-SBI) following a secondary brain injury leading to a ruptured intracranial aneurysm have a poor prognosis
.

Recently, a research article was published in the Journal of Cerebral Blood Flow & Metabolism, the authoritative journal of cerebrovascular and metabolic diseases, which aims to investigate the clinical and pathophysiological relationship between hemoglobin in cerebrospinal fluid (CSF-Hb) and SAH-SBI
.

Blood vessel

In a cohort of 47 patients, the researchers collected CSF samples daily for 14 days after the aneurysm ruptured
.

The relationship between cerebrospinal fluid hemoglobin and secondary brain injury after aneurysmal subarachnoid hemorrhage

There is very strong evidence that there is a positive correlation between CSF-Hb and SAH-SBI measured by spectrophotometry
.

The accuracy of CSF-Hb in monitoring SAH-SBI is significantly better than the established method (AUC: 0.

In general, there is a clinical correlation between high CSF-Hb levels and SAH-SBI.

There is a clinical correlation between high CSF-Hb levels and SAH-SBI.

Original source:

Kevin Akeret.

Cerebrospinal fluid hemoglobin drives subarachnoid hemorrhage-related secondary brain injury in this message

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