It's a good night's sleep, and the risks are not forgotten Breast Cancer Research。

Title: Nighttime eating and breast cancer Chineseamong women in China
Journal:
Mengjie Li, Lap Ah Tse, Wing-cheong Chan, Chi-hei Kwok, Siu-lan Leung, Cherry Wu, Wai-cho Yu, Priscilla Ming-yi Lee, Koon-ho Tsang, Sze-hong Law, Roel Vermeulen, Fangyi Gu, Neil E. Caporaso, Ignatius Tak-sun Yu, Feng Wang and Xiaohong Rose Yang
Published time: 17 Mar, 2017
DOI:
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A new study The metabolic effects of eating late-night snacks may be highly related to breast cancer. The researchers then
the relationship between late-night snacking and breast cancer after 10 p.m. among women in China's
region.recent years, the culture of eating late-night snacks has become more popular. But experimental studies in rats showed that while there was no change in what was eaten, eating at night that should not be eaten led to weight gain in rats, which did not increase in the control rat group who ate at normal times. Epidemiological studies have also shown that eating at night, especially near sleep, is more likely to lead to obesity than eating at other times of the day.
Eating late-night rhythms delays daily eating can lead to changes in neuroendocrine function, including food-regulating proteins such as leptin, growth-releasing peptides and insulin, as well as circadian rhythmic melatonin and cortisol hormones. Eating behavior is also an important time-aging factor for the outer circadian clock (an external factor used to drive the biological rhythm), which is synchronized with the central biological clock in the normal circadian rhythm. Studies have shown that eating at times that don't match the circadian rhythm causes the rodents to have circadian rhythm phase shifts and disorders, and leads to changes in metabolic hormone levels, which may be the cause of obesity-related diseases such as cancer.
, there is very little data on the relationship between night-time eating and breast cancer risk, except for sporadic experimental studies. The results of a U.S. study (National Health and Nutrition Examination Survey, NHANES) show that increased night fasting time is associated with improved blood sugar regulation, which reduces the risk of breast cancer. The purpose of the study, which included comprehensive risk factor data, was to assess the link between night-time eating and breast cancer risk in women through a case-by-case control study of breast cancer.
in a hospital-based case-control study conducted between 2012 and 2015, researchers recruited 922 breast cancer patients (cases) and 913 hospital control participants and surveyed them using standard questionnaires, including dietary behavior information for day and night. The questionnaire included information about eating during the day and at night, such as the point in time, length of time, type of food eaten at night, and frequency of eating. The risk of breast cancer (OR) from variables associated with the nocturnal diet was calculated by unconditional multivariate logical regression.
study found that eating after 10 p.m. was significantly associated with breast cancer, and was more pronounced in women who ate at night for the longest time and at very late hours (midnight to 2 a.m.). Interestingly, the researchers found a link between late-night snacking and breast cancer in women who ate staple foods, and not in women who ate vegetables or fruits as a night meal. In addition, a significant association between late-night eating and breast cancer was found only in women with a body mass index (BMI) <25, which was ≥ in women with a BMI of 25.
, the results showed that nighttime eating was more common in breast cancer patients than in the control group, and there may be a link between eating behavior and breast cancer. These findings require more epidemiological studies, particularly those with forward-looking designs and a large number of subjects, to confirm this association and explore its potential mechanisms.to learn more about Springer Nature's research on breast cancer.。 A novel line of research suggests that eating at nighttime may have several metabolic consequences that are highly relevant to breast cancer. We investigated the association between nighttime eating habits after 10 p.m. and breast cancer in ChinaA hospital-based case-control study was conducted during 2012–2015. A total of 922 patients with incident breast cancer (cases) and 913 hospital controls were recruited and interviewed using a standard questionnaire including information on eating behavior during both daytime and nighttime. We collected the timing, duration, types and frequencies of food intake of eating at nighttime. Odds ratios (ORs) for the risk of breast cancer in relation to nighttime eating-related variables were calculated by unconditional multivariable logistic regression.。 Eating at night after 10 pm was significantly associated with breast cancer with an adjusted OR of 1.50 (95% confidence interval (CI) 1.06–2.12, P = 0.02), and the associations were stronger in women who had the longest duration of nighttime eating (≥20 years) (adjusted OR = 2.28 (95% CI 1.13–4.61, P = 0.02) and who ate late (midnight to 2 a.m.) (adjusted OR = 2.73, 95% CI 1.01–6.99, P = 0.04). Interestingly, nighttime eating was only associated with breast cancer among women who consumed staple foods (OR = 2.16, 95% CI 1.42–3.29, P < 0.001) but not those who ate vegetables or fruits as nighttime meals. The significant association between nighttime eating and breast cancer was observed among women with body mass index (BMI) <25 (OR = 2.29, 95% CI 1.48–3.52, P < 0.001) but not among women with BMI ≥25.。 Results from this study suggest a possible association between nighttime eating behavior and breast cancer. These findings need to be confirmed by independent large studies.
(Source: Science.com)