 Home > Biochemistry News > Biotechnology News > It is expected to control hypertension with one shot in half a year!

It is expected to control hypertension with one shot in half a year!

 Last Update: 2021-12-03
 Source: Internet
 Author: User

Tags

what blood lipids

what food safety

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

On November 8, 2021, Alnylam Pharmaceuticals announced the initiation of a global phase 2 clinical trial to evaluate RNAi therapy zilebesiran (formerly ALN-AGT) in hypertensive patients whose blood pressure cannot be adequately controlled by standard antihypertensive drug therapy.

Hypertension is a complex multi-factor disease.

RNAi (RNA interference) is a natural cellular process of gene silencing, and the discovery of it won the 2006 Nobel Prize in Physiology or Medicine

Zilebesiran is an RNAi therapy targeting mRNA that expresses angiotensinogen

▲Zilebesiran's mechanism of action (picture source: Alnylam official website)

This randomized, double-blind, placebo-controlled Phase 2 clinical trial will enroll approximately 800 adult hypertensive patients who have previously received standard antihypertensive medications

Reference materials:

[1] Alnylam Initiates KARDIA-2 Phase 2 Study of Investigational Zilebesiran (ALN-AGT) in Patients with Inadequately Controlled Hypertension.

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

L-Ascorbate-2-Monophosphate Feed Grade

CAS No.: 109620-90-8

Feed Grade

Potassium Sorbate from reliable manufacturer

CAS No.: 590-00-1

Food Grade

Doxycycline Hydrochloride

CAS No.: 10592-13-9

Pharmaceutical Grade

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.