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Iron deficiency anemia is the most common type of anemia and is a small cell hypochromic anemia caused by insufficient iron storage in the body affecting hemoglobin synthesis
(1) Serum iron
Iron (Fe) is an essential trace element in the human body and is the main raw material
elevated serum iron:
1.
2.
3.
4.
Serum iron decreases:
1.
2.
3.
4.
(2) Serum ferritin
Serum ferritin, referred to as ferritin (Fer), is a soluble tissue protein
@SF is the most sensitive and reliable indicator for the diagnosis of iron deficiency anemia
@ SF can be used to distinguish iron deficiency anemia from anemia with chronic disease
@ SF is an effective indicator for most malignant metastases
(3) Transferrin
Transferrin (TRF) is a glycoprotein in serum β globulin that binds to iron
elevated serum TRF:
Iron deficiency anemia, pregnancy, and tuberculosis
Decreased serum TRF:
Infectious diseases, acute and chronic hepatitis, viral hepatitis, primary liver cancer, nephropathy, uremia, hereditary ferritin deficiency, epidemic hemorrhagic fever, hemochromatosis, aplastic anemia, chronic hemolytic anemia, systemic lupus erythematosus, etc
(4) Total iron-binding force
Total iron-binding capacity (TIBC) is the maximum amount of iron that transferrin can bind per liter of serum and actually reflects the level
elevated serum TIBC:
Iron anemia, acute hepatitis, etc
Decreased serum TIBC:
Cirrhosis, nephropathy, uremia and hemochromatosis
Iron four-item combined test