Interpretation of ginkgo leaf

Ginkgo biloba and its preparation are widely used in the treatment of cardiovascular and cerebrovascular diseases Some elderly people even take Ginkgo biloba for a long time in order to prevent cardiovascular diseases What are the effective ingredients of Ginkgo biloba leaves? Are they suitable for long-term use? Which are the people who are not allowed to take them? With these questions, the reporter interviewed Lin Xiaolan, director of Pharmacy Department of Xuanwu Hospital of Capital Medical University - the leaves of ginkgo tree are ginkgo leaves, which have high medicinal value Ginkgo biloba preparation is a kind of preparation made from Ginkgo biloba as raw material, extracted with proper solvent, and made of Ginkgo biloba extract as raw material Ginkgo biloba extract has more active components, which can be generally divided into flavonoids and lactones It was found that flavonoids in Ginkgo biloba leaves had good effects on circulatory system and brain function The chemical components of Ginkgo biloba extract also include ginkgo acid, which can cause serious allergic reaction, gene mutation and nerve damage In view of this, in 1997, Germany strictly limited the content of silver apricot acid in Ginkgo biloba preparation to below 5ug / g, and the content of silver apricot acid in Ginkgo biloba preparation in 2010 edition of Chinese Pharmacopoeia should be below 10ug / g - the dosage form of Ginkgo biloba preparation is widely favored by patients with cardiovascular and cerebrovascular diseases because of its flat nature At present, there are many dosage forms of Ginkgo biloba preparation on the market, mainly including oral dosage form and injection The oral dosage forms also include tablets, dispersible tablets, granules, capsules, dew, drops, tinctures, oral liquids, soft capsules, dropping pills, etc.; Ginkgo biloba injection includes Ginkgo biloba lactone and ginkgo diterpenoid lactone glucosamine injection, Shuxuening and ginado injection, Ginkgo biloba Damo injection Due to the uneven quality of Ginkgo biloba extract in the market, the price of Ginkgo biloba extract varies greatly due to the different control of ginkgo acid content The difference in drug price is mainly related to the process extraction method, extraction purity, dosage form, brand value, etc - taboos Because Ginkgo biloba leaf can inhibit platelet coagulation function, and excessive long-term use is easy to cause bleeding diseases, it is not suitable to take it in large doses for a long time When it is used together with aspirin, warfarin and other antiplatelet drugs, attention should be paid to the interaction, regular monitoring of thrombinogen time and other indicators, and timely adjusting the dosage under the guidance of doctors to avoid causing bleeding diseases Disease It should be noted that if the patients with hypertension are only general hypertension, there is no stasis syndrome, and the patients' coagulation function is poor, then Ginkgo biloba preparation will cause bleeding Therefore, patients with hypertension must be more cautious when using ginkgo preparations The lancet, an authoritative British Medical Journal, specially reminds elderly patients to use gingko leaves with caution It is not allowed to take Ginkgo biloba leaves for a long time for the patients with senile vascular sclerosis and crispness In addition, because Ginkgo biloba leaves contain toxic ingredients such as ginkgolic acid, it is not advisable to directly pick Ginkgo biloba leaves and take them in water.