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Int J Urol: A survey of predictors of survival outcomes for first-line treatment in metastatic castration-resistant prostate cancer

 Last Update: 2021-11-02
 Source: Internet
 Author: User

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ADT is effective for hormone-sensitive prostate cancer, but most recurrent or advanced prostate cancer is CRPC

Previous studies have shown that docetaxel and ARPIs can prolong survival.

Recently, researchers from Japan published an article in "Int J Urol" to investigate the predictors of survival in patients with metastatic castration-resistant prostate cancer treated with an androgen receptor pathway inhibitor or docetaxel

We investigated the predictors of survival in patients with metastatic castration-resistant prostate cancer treated with an androgen receptor pathway inhibitor or docetaxel.

The study included Japanese patients with metastatic castration-resistant prostate cancer who were treated with an androgen receptor pathway inhibitor or docetaxel between 2008 and 2018

Among the 254 patients with metastatic castration-resistant prostate cancer, 119 (46.

Progression-free survival analysis

In summary, compared with docetaxel, androgen receptor pathway inhibitors have a better prognosis

Compared with docetaxel, androgen receptor pathway inhibitors have a better prognosis

Original source:

Masaki Shiota, Leandro Blas, Satoshi Kobayashi et al.

Predictive factors of survival outcomes in first-line therapy for metastatic castration-resistant prostate cancer

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