Int J Epidemiol: Trends in the incidence of central nervous system tumors in children worldwide, 1988-2012

Globally, central nervous system (CNS) tumors account for about 20% of childhood cancers.
with the progress of science and technology, medical progress, improvement of living environment and so on, the occurrence of CDS tumors in children has changed with time and region. Regional national researchers who included age-standardized morbidity analysis retrieved CNS tumors in the Cancer (CI5) database on five continents and assessed the age-standardized incidence of children aged 0-19 years (ASR, case/1 million), the ratio of male to female incidence (IRR) and the change in the average annualized incidence (AAPC).
tumors included are: asstaryctic cell tumors, cystoblastomas, cystoblastomas, less protrusive glioblastomas and hybrid gliomas, gliomas from unknown sources, and other embryonic tumors.
asR analysis of different tumors in different regions included 56,468 CNS tumors.
the highest ASR in the world in 2012 (5.83,95% CI 5.68-5.99).
incidence of astromas in different regions of the united States is higher than that of men and women worldwide, and the incidence of tumors in this analysis is higher than that of men.
region, only the male-female ratio (IRR) of neuroblastoma continued to rise, between 1.4 and 2.2.
Globally estimated AAPC incidence in the Broad Assessment Equation (GEE) model, the global incidence of astrological cell tumors decreased (AAPC: -1.66), resulting in an increase in the incidence of neuroblastoma, cervosarcoma, gliomas from unknown sources, and other embryonic tumors (AAPC was 0.66, 1.49, 4.76, and 3.58, respectively).
there are some differences in morbidity between regions.
incidence of CNS tumors did not change over time in countries with low human development index (HDI) to high HDI.
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