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Int J Cancer: The addition of high-risk HPV testing to cytology can detect pre-invasive cervical lesions earlier

 Last Update: 2021-04-22
 Source: Internet
 Author: User

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High-risk HPV infection is the main cause of cervical cancer.

Infection screening

Recently, researchers conducted a prospective randomized controlled trial and conducted two rounds of screening to evaluate the effect of HPV testing and body fluid cytology (LBC) combined testing and LBC alone in cervical cancer screening in the Chinese population.

The study included 15,955 women aged 30-60 years, who were randomly divided into an intervention group (HPV and LBC testing) and a control group (LBC testing).

The results showed that compared with the control group, the detection rate of cervical intraepithelial neoplasia (CIN2+) lesions in the intervention group was significantly higher than that in the control group (0.

In summary, the results of this study show that the addition of high-risk HPV testing to the cytological examination of the initial cervical screening can detect clinically significant pre-invasive lesions earlier, thereby reducing the detection rate of subsequent rounds of CIN2+ lesions.

Original source:

Karen KL Chan, et al.

ncbi.
nlm.
nih.
gov/31922265/" target="_blank" rel="noopener">Primary HPV testing with cytology versus cytology alone in cervical screening-A prospective randomized controlled trial with two rounds of screening in a Chinese populatio in this message

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