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Pharmaceutical Network Technical Article: Dry legal particle machine is a kind of swinging effect with rotating roller, through wire sieve can be used to develop moist powder raw materials into particles, is now widely used in pharmaceutical and other industries
Depending on the use, the dry-method granulation machine can be divided into production and experimental Among them, experimental dry legal particle machine is mainly used in the development, development and production of small-dose Chinese medicine preparations in the Drug Research Institute, some of the equipment on the market can achieve clean and closed production from powder to particles, and the human-machine interface is safe, reliable, fast, and the amount of information is large, the yield of the particles is high At the same time transparent workspace design, so that observation more direct and convenient
At present, some domestic dry legal machine manufacturers in the absorption of imported models on the basis of the development of a new type of dry legal system granulated machine, suitable for a variety of materials production, and the system provides from equipment, technology to operators of multi-level password management control, easy to operate safely equipment, production management and product quality control, in the previous drug exhibition widely favored by the audience
No matter what type of dry rule of law granules, operators in the process of use is inevitable need to face the occurrence of some common failures, timely find out the problem to deal with the corresponding
Among them, the amount of dust production is a lot of users have a deep understanding of the problem So why is this happening? There are technical manufacturers to make a brief analysis of this
First, the problem of equipment structure design It is understood that, because many dry legal particle machine manufacturers will be relatively simple design of equipment, did not consider the problem of dust particles, so that the production of equipment is very large, to the user's production and other impact
With the improvement of GMP requirements, the introduction of cGMP concept, dry legal particle factory manufacturers also need to be updated from the specifications and concepts of pharmaceutical production, in the structure needs to be adjusted, fully consider the production of drugs produced dust particles, to ensure the production environment to adapt to the pharmaceutical industry's high-quality development requirements
Technicians also remind that there is also a need to pay attention to the issue of dust production, is the vibration of the equipment "Vibration increases the production of dust particles, increasing the spread of dust particles, so when manufacturing equipment, you need to consider from the overall structure, manufacturing accuracy to find the vibration source that causes vibration, thereby reducing the vibration generated by the equipment."
Second, degassing is not good It is understood that the air in the particle gap is compressed, in the breaking of grain, the pressure suddenly released, gas explosion caused a large number of fine powder, so the yield of dust is larger
In addition to the problem of high dust production, roll wear is also one of the common faults It is understood that the inside of the roll has cooling water, rotating rollers and static cooling pipes on the road there is a mobile sealing device, if used for a long time, it is easy to leak or roll breakage problems At present, some manufacturers have improved the roll structure, so that cooling water directly to the surface of the pressure wheel, can effectively reduce the temperature of the roll surface, but also greatly reduce the possibility of leakage
In addition, due to material selection and processing process reasons, many rollers in use, due to the pressure of grain-making, after a period of use, rollers will also appear wear and other conditions, so many manufacturers after a period of use need to buy roll again.