Improving gut flora ecology may ease the course of liver and kidney disease

China is a big country with liver and kidney diseas. According to the 2019 Annual Report of China Cancer Registry, there were about 365,000 new cases of malignant tumors in China in 2015, accounting for 50% of new cases in the world; data show that in 2020, including chronic hepatitis, fatty liver and liver cirrhosis, China The number of patients with chronic liver disease may exceed 447 million; in 2017, the famous medical journal "The Lancet" published a study titled "The burden of chronic kidney disease in different countries and regions in the world from 1990 to 2017: A systematic analysis of the global burden of disease in 2017", Research shows that there are 695 million chronic kidney disease (CKD) patients worldwide, of which nearly one-third of CKD patients are in China and India, with 132 million and 115 million, respective. In layman's terms, one out of every four people in our country suffers from liver disease, and one out of every 10 people suffers from kidney disea. The findings suggest that a direct dialogue between gut microbes and the brain may take place (hypothalamic neurons directly detect changes in gut bacterial activity) to regulate appetite and temperatu. This excellent article in the journal "gut-brain axis" is another strong piece of evidence that the gut microbiota affects the human bo. In fact, the human body not only has the "gut-brain axis", but also has the "gut-kidney axis" and "gut-liver axis" which are also connected by the intestinal flo. In short, the gut can affect people's liver and kidney health through gut flo. The "gut-kidney axis" refers to the interaction between the gut and kidne. The core theory of the "gut-kidney axis" revolves around chronic kidney disease: in the process of disease progression, intestinal microecological disturbances and intestinal flora imbalances are often accompanied by a decrease in beneficial bacteria and an increase in pathogenic bacter. Exacerbating the accumulation of gut-derived urea toxins in the blood, increasing the burden on the already damaged kidneys, and further reducing renal function; imbalanced intestinal flora will destroy the integrity of the intestinal barrier, leading to gut-derived urea toxins and opportunistic pathogenesis Bacteria translocate into blood circulation, activate intestinal mucosal immunity, induce systemic micro-inflammatory response, and aggravate kidney dama. In the field of kidney disease, there is a well-known strain of Lactobacillus casei Zhang in the wor. Its research report was published in Cell Metabolism (IF=2287), a sub-journal of the world's four famous journals "Cell" and an international journal in the field of metaboli. ) and slow down the development of chronic kidney disease; Phase 1 clinical studies on patients with chronic kidney disease (stages 3-5) have shown that Lactobacillus casei Zhang is safe and beneficial to the human body and can alleviate the decline in renal function in patients; Lactobacillus casei Zhang can improve intestinal flora by improving the , Elevate serum and kidney short-chain fatty acids (SCFAs) and nicotinamide levels to reduce kidney damage and slow the progression of chronic kidney disea. It is worth mentioning that this probiotic is a pure "Chinese bacteri. It was isolated from the Xilin Gol Prairie, Inner Mongolia, in 2002 and naturally fermented yogu. It is also the first lactic acid bacteria in China to complete the whole genome sequenci. The liver and the intestine have the same embryological orig. The liver maintains a direct input and output relationship with the intestine through the portal venous system and the bile duct system, respective. 70%-80% of the blood supply to the liver comes from the intesti. In the "gut-liver axis", the liver transports bile acids and antibacterial molecules to the intestinal lumen through the bile duct to maintain the balance of intestinal flora; on the other hand, intestinal products such as intestinal flora metabolites and related molecules pass through the portal ve. Translocated to the liver, affecting liver functi. To recap, the gut and liver can be influenced in both directions by the gut microbio. From the perspective of practical application, we can judge whether there is a problem with the liver through some changes in the intestinal flora; some problems with the liver can also be assisted by ingesting probioti. Several outstanding Chinese strains currently preserved in the National Culture Bank have a good adjuvant treatment effect on alcoholic liver injury and fatty liver: Probiotic Bifidobacterium lactis Probio-M8, a breast milk-derived probiotic, significantly reduced liver lipid levels in the experime. The level of malondialdehyde (MDA), an oxidized product, showed a relieving effect on alcoholic liver injury, and Lactobacillus plantarum P-8 also showed this potential; Bifidobacterium lactis V9 was shown to assist berberine treatment and improve the Hepatic lobular structure, alleviate liver steatos. The cause of liver and kidney disease is generally bad living habi. For most people, it is especially important to maintain a good habit of going to bed early and getting up early, eating lightly, and doing regular outdoor exerci. In addition, daily supplementation of appropriate probiotics is also an effective measure to prevent liver and kidney diseases and assist in the treatment of liver and kidney diseas. (He Guoqing, Vice Chairman of Probiotics Branch of China Society of Food Science and Technology, Professor of Zhejiang University)   Disclaimer: This article only represents the author's personal opinion and has nothing to do with China Probiotics Netwo. Its originality and the text and content stated in the text have not been verified by this site, and this site does not make any guarantee or commitment to the authenticity, completeness and timeliness of this text and all or part of its content and te. Readers are only for reference and please Verify the relevant content yourse. Copyright Notice Some articles reproduced on this site are not original, and their copyright and responsibility belong to the original auth. 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China is a big country with liver and kidney diseas.

According to the 2019 Annual Report of China Cancer Registry, there were about 365,000 new cases of malignant tumors in China in 2015, accounting for 50% of new cases in the world; data show that in 2020, including chronic hepatitis, fatty liver and liver cirrhosis, China The number of patients with chronic liver disease may exceed 447 million; in 2017, the famous medical journal "The Lancet" published a study titled "The burden of chronic kidney disease in different countries and regions in the world from 1990 to 2017: A systematic analysis of the global burden of disease in 2017", Research shows that there are 695 million chronic kidney disease (CKD) patients worldwide, of which nearly one-third of CKD patients are in China and India, with 132 million and 115 million, respective.

In layman's terms, one out of every four people in our country suffers from liver disease, and one out of every 10 people suffers from kidney disea.

The findings suggest that a direct dialogue between gut microbes and the brain may take place (hypothalamic neurons directly detect changes in gut bacterial activity) to regulate appetite and temperatu.

This excellent article in the journal "gut-brain axis" is another strong piece of evidence that the gut microbiota affects the human bo.

In fact, the human body not only has the "gut-brain axis", but also has the "gut-kidney axis" and "gut-liver axis" which are also connected by the intestinal flo.

In short, the gut can affect people's liver and kidney health through gut flo.

The "gut-kidney axis" refers to the interaction between the gut and kidne.

The core theory of the "gut-kidney axis" revolves around chronic kidney disease: in the process of disease progression, intestinal microecological disturbances and intestinal flora imbalances are often accompanied by a decrease in beneficial bacteria and an increase in pathogenic bacter.

Exacerbating the accumulation of gut-derived urea toxins in the blood, increasing the burden on the already damaged kidneys, and further reducing renal function; imbalanced intestinal flora will destroy the integrity of the intestinal barrier, leading to gut-derived urea toxins and opportunistic pathogenesis Bacteria translocate into blood circulation, activate intestinal mucosal immunity, induce systemic micro-inflammatory response, and aggravate kidney dama.

In the field of kidney disease, there is a well-known strain of Lactobacillus casei Zhang in the wor.

Its research report was published in Cell Metabolism (IF=2287), a sub-journal of the world's four famous journals "Cell" and an international journal in the field of metaboli.

) and slow down the development of chronic kidney disease; Phase 1 clinical studies on patients with chronic kidney disease (stages 3-5) have shown that Lactobacillus casei Zhang is safe and beneficial to the human body and can alleviate the decline in renal function in patients; Lactobacillus casei Zhang can improve intestinal flora by improving the , Elevate serum and kidney short-chain fatty acids (SCFAs) and nicotinamide levels to reduce kidney damage and slow the progression of chronic kidney disea.

It is worth mentioning that this probiotic is a pure "Chinese bacteri.

It was isolated from the Xilin Gol Prairie, Inner Mongolia, in 2002 and naturally fermented yogu.

It is also the first lactic acid bacteria in China to complete the whole genome sequenci.

The liver and the intestine have the same embryological orig.

The liver maintains a direct input and output relationship with the intestine through the portal venous system and the bile duct system, respective.

70%-80% of the blood supply to the liver comes from the intesti.

In the "gut-liver axis", the liver transports bile acids and antibacterial molecules to the intestinal lumen through the bile duct to maintain the balance of intestinal flora; on the other hand, intestinal products such as intestinal flora metabolites and related molecules pass through the portal ve.

Translocated to the liver, affecting liver functi.

To recap, the gut and liver can be influenced in both directions by the gut microbio.

From the perspective of practical application, we can judge whether there is a problem with the liver through some changes in the intestinal flora; some problems with the liver can also be assisted by ingesting probioti.

Several outstanding Chinese strains currently preserved in the National Culture Bank have a good adjuvant treatment effect on alcoholic liver injury and fatty liver: Probiotic Bifidobacterium lactis Probio-M8, a breast milk-derived probiotic, significantly reduced liver lipid levels in the experime.

The level of malondialdehyde (MDA), an oxidized product, showed a relieving effect on alcoholic liver injury, and Lactobacillus plantarum P-8 also showed this potential; Bifidobacterium lactis V9 was shown to assist berberine treatment and improve the Hepatic lobular structure, alleviate liver steatos.

The cause of liver and kidney disease is generally bad living habi.

For most people, it is especially important to maintain a good habit of going to bed early and getting up early, eating lightly, and doing regular outdoor exerci.

In addition, daily supplementation of appropriate probiotics is also an effective measure to prevent liver and kidney diseases and assist in the treatment of liver and kidney diseas.

(He Guoqing, Vice Chairman of Probiotics Branch of China Society of Food Science and Technology, Professor of Zhejiang University)

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China is a big country with liver and kidney diseas.

According to the 2019 Annual Report of China Cancer Registry, there were about 365,000 new cases of malignant tumors in China in 2015, accounting for 50% of new cases in the world; data show that in 2020, including chronic hepatitis, fatty liver and liver cirrhosis, China The number of patients with chronic liver disease may exceed 447 million; in 2017, the famous medical journal "The Lancet" published a study titled "The burden of chronic kidney disease in different countries and regions in the world from 1990 to 2017: A systematic analysis of the global burden of disease in 2017", Research shows that there are 695 million chronic kidney disease (CKD) patients worldwide, of which nearly one-third of CKD patients are in China and India, with 132 million and 115 million, respective.

In layman's terms, one out of every four people in our country suffers from liver disease, and one out of every 10 people suffers from kidney disea.

The findings suggest that a direct dialogue between gut microbes and the brain may take place (hypothalamic neurons directly detect changes in gut bacterial activity) to regulate appetite and temperatu.

This excellent article in the journal "gut-brain axis" is another strong piece of evidence that the gut microbiota affects the human bo.

In fact, the human body not only has the "gut-brain axis", but also has the "gut-kidney axis" and "gut-liver axis" which are also connected by the intestinal flo.

In short, the gut can affect people's liver and kidney health through gut flo.

The "gut-kidney axis" refers to the interaction between the gut and kidne.

The core theory of the "gut-kidney axis" revolves around chronic kidney disease: in the process of disease progression, intestinal microecological disturbances and intestinal flora imbalances are often accompanied by a decrease in beneficial bacteria and an increase in pathogenic bacter.

Exacerbating the accumulation of gut-derived urea toxins in the blood, increasing the burden on the already damaged kidneys, and further reducing renal function; imbalanced intestinal flora will destroy the integrity of the intestinal barrier, leading to gut-derived urea toxins and opportunistic pathogenesis Bacteria translocate into blood circulation, activate intestinal mucosal immunity, induce systemic micro-inflammatory response, and aggravate kidney dama.

In the field of kidney disease, there is a well-known strain of Lactobacillus casei Zhang in the wor.

Its research report was published in Cell Metabolism (IF=2287), a sub-journal of the world's four famous journals "Cell" and an international journal in the field of metaboli.

) and slow down the development of chronic kidney disease; Phase 1 clinical studies on patients with chronic kidney disease (stages 3-5) have shown that Lactobacillus casei Zhang is safe and beneficial to the human body and can alleviate the decline in renal function in patients; Lactobacillus casei Zhang can improve intestinal flora by improving the , Elevate serum and kidney short-chain fatty acids (SCFAs) and nicotinamide levels to reduce kidney damage and slow the progression of chronic kidney disea.

It is worth mentioning that this probiotic is a pure "Chinese bacteri.

It was isolated from the Xilin Gol Prairie, Inner Mongolia, in 2002 and naturally fermented yogu.

It is also the first lactic acid bacteria in China to complete the whole genome sequenci.

　　The liver and the intestine have the same embryological orig.

The liver maintains a direct input and output relationship with the intestine through the portal venous system and the bile duct system, respective.

70%-80% of the blood supply to the liver comes from the intesti.

In the "gut-liver axis", the liver transports bile acids and antibacterial molecules to the intestinal lumen through the bile duct to maintain the balance of intestinal flora; on the other hand, intestinal products such as intestinal flora metabolites and related molecules pass through the portal ve.

Translocated to the liver, affecting liver functi.

To recap, the gut and liver can be influenced in both directions by the gut microbio.

From the perspective of practical application, we can judge whether there is a problem with the liver through some changes in the intestinal flora; some problems with the liver can also be assisted by ingesting probioti.

Several outstanding Chinese strains currently preserved in the National Culture Bank have a good adjuvant treatment effect on alcoholic liver injury and fatty liver: Probiotic Bifidobacterium lactis Probio-M8, a breast milk-derived probiotic, significantly reduced liver lipid levels in the experime.

The level of malondialdehyde (MDA), an oxidized product, showed a relieving effect on alcoholic liver injury, and Lactobacillus plantarum P-8 also showed this potential; Bifidobacterium lactis V9 was shown to assist berberine treatment and improve the Hepatic lobular structure, alleviate liver steatos.

　　The cause of liver and kidney disease is generally bad living habi.

For most people, it is especially important to maintain a good habit of going to bed early and getting up early, eating lightly, and doing regular outdoor exerci.

In addition, daily supplementation of appropriate probiotics is also an effective measure to prevent liver and kidney diseases and assist in the treatment of liver and kidney diseas.

(He Guoqing, Vice Chairman of Probiotics Branch of China Society of Food Science and Technology, Professor of Zhejiang University)

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