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The correlation between blood pressure (BP) and hypertension and different types of brain injury in patients with atrial fibrillation is not clear.
, researchers obtained a patient's BP value from a queue of patients with multi-center atrial fibrillation, according to a recent study published in hypertension, an authoritative journal of cardiovascular disease.
were classified for systolic and espressosis according to a predetermined group, and all patients underwent MRI and neurocognitive testing.
brain lesions are divided into large non-cortological or cortological infarctions, small non-cortological infarctions, micro-bleeding or white lesions.
researchers graded white lesions based on the Fazekas scale.
, the cross-sectional analysis included 1,738 patients with atrial fibrillation (the average age was 73 years, with 73 per cent of men).
average blood pressure was 135/79 mmHg, and 67% of the participants were receiving blood pressure reduction therapy.
researchers found that 54 percent of patients with white lesions fazekas≥22 percent had large non-cortological or cortological infarction, 21 percent had small non-cortological infarctions, and 22 percent had micro-bleeding.
the correction ratio (95%CI) was 1.2% for patients with systolic pressure of 120 to 140, 140 to 160 and ≥160 mmHg for patients with systolic pressure≥ and 120 mmHg 25 (0.94-1.66), 1.41 (1.03-1.93) and 2.54 (1.65-3.95) (linear trend P.lt;0.001).
systolic and espressure pressure increased by 5 mmHg, the adjusted β coefficient (95%CI) of the dexterity-converted white lesions was 0.04 (0.02-0.05), P.lt;0.001 and 0.04 (0.01-0.06), respectively.
systolic blood pressure is associated with smaller non-cortial infarction (the ratio of 5mmHg per increase is 1.05 (1.01-1.08), and micro-bleeding is associated with hypertension, but larger non-cortial or cortial infarction is not associated with blood pressure or hypertension.
, blood pressure and hypertension were independent of neurocognitive function.
, it can be seen that bp is closely related to white matter lesions and their degree in patients with atrial fibrillation, but not to large non-cortological or cortial infarctions.
