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Hypertension: Long-term blood pressure variability increases the risk of dementia and cognitive decline

 Last Update: 2021-08-27
 Source: Internet
 Author: User

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Hypertension (BP) is considered to be an important risk factor for cognitive impairment and dementia
.

Regardless of the blood pressure level, blood pressure variability (BPV) may cause cognitive decline and even dementia

Recently, the heart blood vessels authoritative magazine published a research article on Hypertension, the study was designed to explore whether BPV is an independent predictor of cognitive impairment or dementia
.

Heart blood vessels

The researchers searched the MEDLINE, Embase, PsycINFO, CINAHL and Web of Science databases, and the search time is up to May 2021
.

The researchers included longitudinal studies that used BPV as a predictor to assess the risk of dementia or cognitive impairment, and used meta-analysis and meta-regression to assess the impact of BPV on the risk of dementia or cognitive impairment

Follow-up dose-response relationship between systolic blood pressure variability (SBPV) and dementia and cognitive impairment

The researchers identified a total of 5919 papers, including 16 longitudinal studies, with a total of 7 million participants.
The median age of the participants ranged from 50.
9 to 79.
9 years, and the median follow-up time was about 4 years
.

Thirteen studies reported on follow-up BPV and found that systolic BPV increased the risk of dementia, with a combined hazard ratio of 1.

It can be seen that long-term BPV is an independent risk factor for cognitive impairment or dementia, so the intervention plan to reduce BPV can be used as a target for early prevention of dementia
.

Long-term BPV is an independent risk factor for cognitive impairment or dementia, so an intervention plan to reduce BPV can be used as a target for early prevention of dementia
.

prevention

Original source:

Pingping Jia.

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