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Orthostatic hypotension ( OH ) is a common symptom in the elderly, which reflects changes in hemodynamics and body position
Orthostatic hypotension ( OH ) is a common symptom in the elderly, which reflects changes in hemodynamics and body position
However, the clinical manifestations of patients with OH are quite different.
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pixabayThe clinical manifestations of OH are related to hypoperfusion of various organs.
The clinical manifestations of OH are related to hypoperfusion of various organs.
Recently, a study published in the journal Hypertension Hypertension showed that OH is associated with an increased risk of dementia, even in the absence of OH symptoms .
In this study, the researchers used data from the Swedish National Kungshomen Aging and Care Study (SNAC-K) , which regularly followed up approximately 2500 subjects (age ≥ 60 years)
In this study, the researchers used data from the Swedish National Kungshomen Aging and Care Study (SNAC-K) , which regularly followed up approximately 2500 subjects (age ≥ 60 years)
It was found that during the 12- year follow-up period, 322 ( 12.
The relationship between orthostatic hypotension (OH) and the incidence of dementia
Further analysis of OH-related symptoms showed that compared with asymptomatic OH , symptomatic OH has a stronger correlation with dementia; however, after adjusting for all confounding factors, the association with symptomatic OH is no longer significant
Further analysis of OH-related symptoms showed that, compared with asymptomatic asymptomatic OH , symptomatic OH is more correlated with dementia; however, after adjusting for all confounding factors, the correlation with symptomatic OH is no longer significant
Sensitivity analysis showed that when a more stringent definition was used to define OH , there was a stronger correlation between OH and dementia, AD and CIND progressing to dementia, and AD OH and dementia, AD and CIND progressing to dementia and AD .
The relationship between asymptomatic and symptomatic orthostatic hypotension (OH) and cognitive function
The relationship between asymptomatic and symptomatic orthostatic hypotension (OH) and cognitive functionIn addition, when OH is classified according to the possible causes , the results show that both non-neurogenous and neurogenic OH are significantly associated with an increased risk of dementia, while only non-neurogenic OH is significantly associated with CIND progression to dementia and AD .
In addition, when OH is classified according to the possible causes , the results show that both non-neurogenous and neurogenic OH are significantly associated with an increased risk of dementia, while only non-neurogenic OH is significantly associated with CIND progression to dementia and AD .
In short, the elderly should actively evaluate their postural blood pressure, which is especially important, because orthostatic hypotension is usually asymptomatic.
Original source
Xin Xia et al, From Normal Cognition to Cognitive Impairment and Dementia: Impact of Orthostatic Hypotension , Hypertension (2021).
Xin Xia et al, From Normal Cognition to Cognitive Impairment and Dementia: Impact of Orthostatic Hypotension , From Normal Cognition to Cognitive Impairment and Dementia: Impact of Orthostatic Hypotension Hypertension Hypertension (2021).
DOI: 10.
1161/HYPERTENSIONAHA.
121.
17454 DOI: 10.
1161/HYPERSION .
121.
17454
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