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Humanized yeast: Scientists create yeast with important human genes

 Last Update: 2022-08-15
 Source: Internet
 Author: User

Humans and yeast are similar

According to Daran-Lapujade, there are many similarities between yeast and humans: "It may seem strange because yeast is a single-celled life, whereas humans are made up of an inherently more complex system, but cells are very similar in the way it wor.

Daran-Lapujade explained: "Compared to human cells or tissues, yeast is an amazing creature because of its simplicity of growth and its genetic accessibility: its DNA can be easily modified to solve fundamental proble.

humanized yeast

Daran-group Lapujade has previously successfully engineered artificial chromosomes as a DNA platform to build new functions in yea.

Daran-Lapujade explained: "We not only transplanted human genes into yeast, but also removed the corresponding yeast genes and completely replaced them with human muscle gen.

further humanization

The researchers collaborated with Pr.

This process is only a small part of human metabolism; there are many similar processes between yeast and human cells that can be studied in humanized yea.

"This is just a starting point," she sa.

Reference: "Full humanization of the glycolytic pathway in Saccharomyces cerevisiae" by Francine.

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