How to scientifically reduce hormones in SLE patients?

Hormones play a vital role in the treatment of SLE, but at the same time, butterfly friends also have certain concerns: if large doses of hormones are given, they are worried about the adverse reactions caused by long-term use, and if the dose of hormones is not increased, they are worried about the recurrence of the disease
.

How does SLE scientifically reduce hormones? Stop and reduce properly, in order to master the "destiny"

 

Image source: Photo Network Genuine Gallery

Why do you need to reduce hormones after your condition is stable?Glucocorticoids (GC, hereinafter referred to as hormones) are all too familiar to those with systemic lupus erythematosus (SLE)
.

At present, hormones are still one of the main treatment methods.
The "2020 White Paper on the Quality of Life of Chinese Lupus Erythematosus Patients" shows that more than 90% of the butterfly friends have received hormone therapy , followed by antimalarial drugs, immunosuppressants and biological agents.

We hate and love hormones

Moderate activity, moderate doses of hormones (0.
5-1 mg·kg-1·d-1) prednisone or equivalent doses of other hormones are recommended
.

Immunosuppressive agents can be used in combination to reduce the cumulative dose of hormones and reduce the risk of long-term adverse effects

For severe activity, it is recommended to use standard doses of hormones (1 mg·kg-1·d-1 prednisone or equivalent doses of other hormones) combined with immunosuppressive agents for treatment, and adjust the dose of hormones after the disease is stable
.

At the same time, for the butterfly friends who are seriously ill, hormone pulse therapy can be used if necessary

If you are a butterfly friend with a long-term stable condition, you can start considering hormone reduction as soon as possible
.

 

Image source: Photo Network Genuine Gallery

The reduction of hormones is a slow process.
If some abnormal conditions occur during the reduction, such as infection , you can consider increasing hormones to relieve such symptoms
.

After the dose reduction, closely observe your own physical condition.

Relapse is a common clinical feature of SLE patients, and studies have shown that the overall 4-year risk of recurrence in SLE patients is 60%

How does SLE scientifically reduce hormones? Stop and reduce properly, in order to master the "destiny"

If you want to master "destiny", you can't do without the escort of professional knowledge.
Since 2020, there have been more and more discussions on hormone therapy related to systemic lupus erythematosus .

Image source: Photo Network Genuine Gallery

Image source: Photo Gallery Genuine Gallery Why do you need to reduce hormones after your condition is stable? More than 90% of the butterfly friends have received hormone therapy More than 90% of the butterfly friends have received hormone therapy immunization

Image source: "2020 White Paper on the Quality of Life of Chinese Lupus Erythematosus Patients"

Image source: "2020 White Paper on the Quality of Life of Chinese Lupus Erythematosus Patients" How to properly reduce hormone doses in Osteoporosis , Diabetes , Hypertension and SLE? Each dose of hormones is like the next step, gradually and regularly

Mild activity generally does not require hormone therapy
.

When hydroxychloroquine or non-steroidal anti-inflammatory drugs cannot control the disease, low-dose hormones (prednisone ≤10 mg/d or equivalent doses of other hormones) can be considered to control the disease 

Moderate activity, moderate doses of hormones (0.
5-1 mg·kg-1·d-1) prednisone or equivalent doses of other hormones are recommended
.
Immunosuppressive agents can be used in combination to reduce the cumulative dose of hormones and reduce the risk of long-term adverse effects
.

For severe activity, it is recommended to use standard doses of hormones (1 mg·kg-1·d-1 prednisone or equivalent doses of other hormones) combined with immunosuppressive agents for treatment, and adjust the dose of hormones after the disease is stable
.
At the same time, for the butterfly friends who are seriously ill, hormone pulse therapy can be used if necessary
.

If you are a butterfly friend with a long-term stable condition, you can start considering hormone reduction as soon as possible
.

 

Image source: Photo Network Genuine Gallery

Image source: Photo Gallery Genuine Gallery Infection If you feel that the condition is unstable and easy to rebound, you can consider what kind of hormone reduction is successful if you no longer continue to reduce the dose? What kind of hormone reduction is considered successful? The condition of SLE patients must be stable on the basis of the fact that after the recurrence and rebound factors are removed, the condition is still stable after the dose reduction to be considered successful.

The current consensus of SLE is to control the disease in an ideal state of clinical stability.
If clinical stability cannot be achieved, the disease activity should also be controlled at the lowest possible level of disease activity to reduce recurrence and reduce adverse drug reactions
.

The consensus 4-year overall recurrence risk for SLE patients was 60%
.
Therefore, everyone still needs to use it correctly according to the doctor's guidance, and the increase or decrease of the drug needs to be carried out in accordance with the doctor's order
.
leave a message here