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Researchers at Linkping University in Sweden have discovered a biological mechanism that increases the intensity
of fear memory stored in the brain.
The ability to experience fears is essential for escaping life-threatening situations and learning to avoid them in the
future.
Certain areas of the brain are particularly important
for processing fear-related memories.
"We know that the network of nerve cells that connect the frontal lobe and the amygdala is associated
with fear responses.
However, the molecular mechanisms have remained unknown
.
In order for new memories to last, they must be stabilized and preserved as long-term memories
.
"We have identified a mechanism whereby increased network activity between the frontal lobe and amygdala increases the learned fear response
.
The researchers also identified genes
that are affected when PRDM2 levels are reduced.
"People with anxiety disorders may benefit
from treatments that weaken or eliminate fearful memories.