How can scientists use new blood detection techniques to improve the diagnosis and treatment of a variety of human diseases?
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Last Update: 2020-08-01
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Source: Internet
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Author: User
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this article, the small compilation of a number of research reports, together focus on how scientists how to use new blood detection technology to improve the diagnosis and treatment of a variety of human diseases? Share it with everyone!
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LSA: New biosensor technology or the ability to accelerate blood testing in patients with COVID-19doi: 10.1038/s41377-020-0336-6recently, in a study published in the international journal Light: Science and
, scientists from the University of York and other institutions have developed a new type of sensor technology that can accelerate the development of a new type of blood test for patients. In the article, the researchers used laser technology to develop a handheld biosensor that could provide fast, real-time blood testing for a variety of patients, including patients with secondary infections such as pneumonia, COVID-19.the new technology, which uses laser interferometry (two beams of light combined to form interferon-like images) to detect special proteins such as primary calcitonin, rise in the body when a patient is infected with
bacteria
; Cell: Scientists have developed a new type of blood test or can effectively improve screening of people with liver cancer doi: 10.1016/j.cell.2020.05.038 Recently, scientists from the National Cancer Institute of the United States have developed a new test that can help identify liver cell cancer (HCC), Hepatocellular carcinoma is the most common type of
liver cancer
, a new method that uses simple blood tests to check whether a patient has been exposed to a specific viral infection. When combined with current screening methods, this new test plays an important role in screening people at risk of HCC, helping clinicians to detect and treat HCC as early as possible, a relatively simple and inexpensive new method that requires only a small number of blood samples to be tested, saidresearcher Xin Wei Wang. Specific factors increase an individual's risk of HCC, such as hepatitis B or HCV infection, or cirrhosis, and people with risk factors are often recommended for HCC screening every 6 months, i.e. using ultrasound scans or testing of alpha-A-fetal protein in the blood.
Clin Cancer Res: Breakthrough! New blood testing technology may be able to diagnose pancreatic cancer earlier! doi: 10.1158/0432.CCR-19-3313 a recent study published in the international journal Clinical Cancer Research, scientists from the University of Pennsylvania Perelman School of Medicine and other institutions have developed a new blood test that not only can detect Common pancreatic cancers in the early stages can also help clinicians accurately assess the progression of the disease and treat patients optimally, and in blind studies, this new liquid biomarker technology can detect patients more accurately than any other
biomarker
, while also being able to stage patients' diseases more accurately than alone.pancreatic catheter adenocarcinoma is the most common pancreatic cancer, the third leading cause of death in cancer patients, with an overall five-year survival rate of only 9% and most patients surviving less than a year after diagnosis; For patients with localized disease progression, the cancer does not spread except the pancreas, but according to the size and unknown size of the
tumor
is not suitable for patients undergoing surgery; Science: Blood tests help detect cancerdoi: 10.1126/science.abb9601 before symptoms appear In a new study, researchers from research institutions such as Johns Hopkins University School of Medicine in the United States first found that blood tests help detect multiple cancers in thousands of people without a history or symptoms. The blood test is still experimental. Even its supporters say it needs improvements, and the results are not ideal. However, they show the benefits and disadvantages of using these gene-based tests in routine care, called liquid biopsies--- in which case PET scans are used to identify or exclude suspicious
tumor
, the study was published in the journal Science.to date, many of the current cancer testing tools have been tested on blood samples from people with and without cancer to estimate their accuracy. The new study is the first "real-world" test in routine medicine and tracks patients through surgery or other methods to see how they perform. Nearly 10,000 women between the ages of 65 and 75 with no history of cancer were recruited through the Geisinger Health System in Pennsylvania and New Jersey. That's because some deadly cancers, such as ovarian cancer, don't have screening tests, and women in this age group have a higher risk of cancer and are still young enough to benefit from early detection of cancer, Papadopoulos said.
JPD: Simple blood tests or doi: 10.3233/JPD-191724 In order to provide the best medical care for patients with Parkinson's disease who have newly
diagnosed
, a way to predict their cognitive and motor progression may go beyond simple clinical parameters. A recent study published in the international journal Of Parkinson's, scientists from the University of Newcastle and others, suggested that a blood test that detects inflammatory and cellular aging
biomarkers
may be able to reliably predict cognitive decline in individuals, including identifying early dementia and motor disorders in patients with Parkinson's disease.researcher Dr. Gabriele Saretzki said the cumulative incidence of dementia associated with Parkinson's disease is about 80 percent, and individuals with Parkinson's disease are 5-6 times more likely to develop cognitive impairment than their peer-to-peer counterparts, and That Parkinson's disease is an inflammation-related disease, after researchers found that an inflammatory feature in the blood or a predictor of faster clinical progress in patients.
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Clin
Epigenetic
: Blood tests can detectrisk of Alzheimer's disease: 10.1186/s13148-019-0729-7 in a recent study, researchers found changes in blood sample markers associated with Alzheimer's disease. Based on a study of twins in Finland, one with Alzheimer's disease and the other cognitively healthy, the researchers used the latest genome-wide method to check for disease-related epigenetic
genetic
markers in the twin's blood samples, and how sensitive these differences are to changes in environmental factors. Eventually, the researchers found these differences in several different genomic regions.the extent to which symptoms worsen in the late stages of Alzheimer's disease is influenced by genetic and environmental factors, including lifestyle. Different environmental factors can alter the function of disease-related genes by altering their epigenetic regulation, for example by regulating methylation by DNA that controls the function of genes. By measuring the methylation levels of DNA isolated from blood samples from Finnish twins, researchers found epigenetic
markers associated with Alzheimer's disease in several different genomic regions. One of these markers also appeared stronger in brain samples in patients with Alzheimer's disease. In addition, a study of Swedish twins confirmed a link between the sign and Alzheimer's disease.
Nat Commun: Blood tests can help predict brain cancerdoi: 10.1038/s41467-019-12527-5 scientists at University of Strathclyde have developed a blood test that can help speed up the diagnosis of
in brain cancer
. The technology uses infrared light to create "biocharacteristics" of blood samples and uses artificial intelligence to detect cancer. The findings are now published in the journal Nature Communications. 'This is the first data we have published on a clinical feasibility study, and the first clinical evidence of our blood tests,'researchers said.
diagnosis
brain tumors are often difficult, leading to delays in treatment in many patients. The reason for this is that early symptoms of a brain tumor, including headaches or memory problems, are nonspecific diseases, so it may be difficult for doctors to tell who is most likely to have a brain tumor. :
Immunol: New blood tests may help predict the risk of recurrence of the disease in patients with
breast cancer
doi: 10.1038/s41590-019-0429-7 a recent study published in the international journal Nature Vision, scientists from the Hope City Center for Integrated Cancer Research in the United States have developed a special blood test that could help predict the risk of
new diagnosis of new
. Peter P. Lee, M.D., , noted that for the first time in the study, we linked solid tumors to blood biomarkers,
biomarkers
are indicators that indicate whether a patient's disease is in remission, but it is important to identify patients with a higher risk of recurrence after being diagnosed
as cancer. It makes it easier to treat and monitor patients in the clinic, and
tumor
phases and new detection methods based on tumor genomic analysis can often be used to stratify the risk of disease, but predictive blood testing is often more attractive, but is not widely used, so researchers are trying to see if they can change the current situation. PLoS ONE: Scientists are expected to develop a new blood test for heart disease doi: 10.1371/journal.pone.0211762 in a study published in the international journal PLoS ONE, scientists from Duke University Medical Center said they could develop a new blood test to indicate whether blood entering the heart's arteries is stenosis or blocked.emergency patients who were tested in tread-truck load tests and showed signs of decreased blood flow in the heart typically showed changes in five metabolites within two hours, and the researchers said that all subjects had visited the emergency department and had developed symptoms of coronary heart disease, such as chest pain and shoulder pain;
Sci Transl Med: Scientists have developed a new type of cancer blood detection technology based on the size of DNA fragments doi: 10.1126/scitranslmed.aat4921 , published in the international journal Science Translational Medicine, in a study published in the international journal Science Translational Medicine.
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